Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 40 for “"Dose reduction"”.
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Dose reduction of biologics in psoriasis
Contains fulltext : 240236.pdf (Publisher’s version ) (Open Access)
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Radon remediation: an analysis of dose-reduction, durability and effectiveness
… and questionnaires, to determine occupancy, dose reduction has been calculated for all members of staff in the remediated venues. The reduction in dose is lower than the reduction in radon. The trends in radon levels post-remediation have been investigated night-time levels are reduced more …
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COMPRESSIVE SENSING BASED IMAGE RECONSTRUCTION FOR COMPUTED TOMOGRAPHY DOSE REDUCTION
… is an important strategy to reduce the radiation dose. In the iterative CT reconstruction, the projection / backprojection model plays an important role in the overall computational cost, image quality, and reconstruction accuracy. In this dissertation, we first propose an improved distance-driven …
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Construction and operation of an in-pile loop for PWR dose reduction experiments
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 1990.
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Iterative reconstruction as a novel method of radiation dose reduction at computed tomography in patients with Crohn's disease
… that quantified the alarming levels of radiation dose to patients with Crohn’s disease from medical imaging and the notable shift towards CT imaging making these patients an at risk group, provided context for this work. CT delivers some of the highest doses of ionising radiation in diagnostic …
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A study of the dose reduction benefits of electrostatic precipitation in the capture of radionuclide aerosols produced during decommissioning processes
… if not controlled, can spread and impart a dose to workers and the environment. This work proposes the employment of electrostatic precipitators (ESPs) as area filters that capture radionuclide aerosols produced during nuclear dismantlement. These filtration systems demonstrate advantages in …
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Optimization of image quality and radiation dose in neuroradiological computed tomography
… resolution, is a major limitation for radiation dose reduction in CT. This can be counteracted with new post-processing image filters and iterative reconstruction (IR) algorithms that improve image quality and allow for reduced radiation doses. Implementation of new methods in clinical routine …
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Dosisreduktion in der Multidetektor-Computertomographie
Several dose-reduction strategies were evaluated in this work by phantom- and patient studies.1. The tube-current-modulation system "CareDose 4D" (Siemens Medical Solutions, Forchheim, Germany) enabled a reduction of effective dosage of 56,1% up to 70,1%, depending on the orientation of the …
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Chemoptherapy Dose Reductions in Palliative Lung Cancer. Evaluating Chemotherapy Dose Reductions following Neutropenia in Palliative Lung Cancer to prevent further Adverse Events
… Neutropenia is a life-threatening and dose-limiting toxicity of palliative lung cancer chemotherapy. Whilst some neutropenias are inevitable, evidence suggests that patients with a previous neutropenic event are 50% more likely to have a further neutropenic event. The aim of this …
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Chemoptherapy Dose Reductions in Palliative Lung Cancer. Evaluating Chemotherapy Dose Reductions following Neutropenia in Palliative Lung Cancer to prevent further Adverse Events
… Neutropenia is a life-threatening and dose-limiting toxicity of palliative lung cancer chemotherapy. Whilst some neutropenias are inevitable, evidence suggests that patients with a previous neutropenic event are 50% more likely to have a further neutropenic event. The aim of this …
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Assessment of Collimator Jaw Optimization In Reducing Normal Tissue Irradiation With Intensity Modulated Radiation Therapy
… To evaluate normal tissue dose reduction in step-and-shoot intensity-modulated radiation therapy (IMRT) on the Varian 2100 platform by tracking the multileaf collimator (MLC) apertures with the accelerator jaws.</p> <p><strong>Methods: </strong>Clinical radiation treatment …
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Clinical Drug-Gene and Drug-Drug-Gene Interactions for the Most Commonly Used Chronic Drugs in the UK
… was associated with a 25% (15-44%) lower odds of dose reduction of quinine, p=1.6×10-5; the A-allele at rs9895420 in ABCC3 was associated with a 46% (24-62%) reduction in odds of dose reduction with doxazosin, p=1.2×10-4, and altered blood pressure response in the UK Biobank; the CYP2D6*2 variant …
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A Scheme for Ultra-Fast Computed Tomography Based on Stationary Multi-Beam X-ray Sources
… mainly limited by motion blurring and radiation dose. The conceptual multi-source interior CT scheme has provided a potential solution to reduce motion artifacts and radiation exposure. This dissertation work conducted multi-facet investigations on a novel multi-source interior CT architecture …
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Adolescent Idiopathic Scoliosis. The Role of Low Dose Computed Tomography.
… in daily clinical practice means high radiation dose to these young individuals. All examinations included in this thesis were performed on a 16-slice CT scanner. Examination of the chest phantom in paper I showed that the radiation dose of the spine (including 15 vertebrae) was 20 times lower …
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Microcomputer control of a three-dimensional stereoflouroscope
… PLZT goggles to provide a stereoscopic image. Dose reduction should be obtained through the use of the computer as the controlling mechanism. Two storage tubes will be synchronized with the fluoroscopic apparatus to allow repeated replay of an instantaneous fluoroscopic image. A wide range of …
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Feasibility Study of Low Dose Chest CT for Initial Evaluation of Blunt Chest Trauma Patient
… CT results in rapid increase of the CT radiation dose in blunt chest trauma evaluation. Therefore, according to the ALARA (as low as reasonable achievable) principle, radiation dose adjustment in the patients with blunt chest trauma is inevitable. We aimed to evaluate the diagnostic performance …
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Dual-Criterion Dose Finding Designs for Phase I Clinical Trials
… tolerability of novel therapeutics. Conventional dose escalation methods identify the maximum tolerated dose (MTD) based on dose-limiting toxicity (DLT). However, as cancer therapies have evolved from chemotherapy to targeted therapies, these traditional methods have become problematic. Many …
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Advanced Statistical Modeling for Model-Based Iterative Reconstruction for Single-Energy and Dual-Energy X-Ray CT
… due to its significant advantage in drastic dose reduction without diagnostic loss. Early success of the method in conventional CT has encouraged the extension to a wide range of applications that includes more advanced imaging modalities, such as dual-energy X-ray CT, and more challenging …
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Tomographic reconstruction with adaptive sparsifying transforms
… obstacle in computed tomography (CT) is the reduction of harmful x-ray dose while maintaining the quality of reconstructed images. Methods which exploit the sparse representations of tomographic images have long been known to improve the quality of reconstructions from low-dose data. Recent …
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Cone Beam Computed Tomography - radiation dose and image quality assessments
… reconstruction, image resolution and radiation dose. When new technology is introduced one must make sure that diagnostic accuracy is better or at least as good as the one it can be expected to replace. The CBCT brand tested was two versions of Accuitomo (Morita, Japan): 3D Accuitomo with an …
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