Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Dorsolateral Striatum"”.
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THE EFFECTS OF SOCIAL STRESS AND PRIOR ETHANOL EXPOSURE ON DOPAMINE IN THE RAT BRAIN
… pathways, the nucleus accumbens core and dorsolateral striatum. Experiments revealed an effect of stress through increasing dopamine release per stimulus pulse in the nucleus accumbens core of ethanol-naïve, and not ethanol-exposed, subjects. Furthermore, ethanol administration decreased …
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Changes in the firing patterns in neurons of the sensorimotor striatum during learning : what changes and why
… ganglia, and specifically the sensorimotor (dorsolateral) striatum, have been implicated in stimulus-response learning. Here, I analyze the role the striatum plays in learning. We recorded from neurons of the sensorimotor striatum as rats learn, are over-trained, are extinguished, and are …
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Development of and proposed applications for tetrodes in functional mapping of rodent sensorimotor striatum
… adapted by a group of investigators for use in dorsolateral striatum. Measures were taken to improve the reliability of reaching the target area in the brain and the stability of the implanted tetrode drive over several weeks of recording. Novel methods were developed to confirm the dorsoventral …
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Characterizing corticostriatal circuit function during performance of habitual action sequences
The striatum is the largest nucleus in the basal ganglia and the recipient of dense dopamine input. Multiple cortico-basal ganglia-thalamic loops are thought to function together during the learning and performance of reinforced behaviors, with the dorsolateral circuit being particularly critical …
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Probing the Mechanisms of Reinforcement Learning: Reinforcement Learning, Ventral Striatal Astrocytes, and the Dynamic Coordination of Information Seeking with Learning
… and attenuated the astrocyte activity in Ventral Striatum (VS), Dorsolateral Striatum (DLS), and Dorsomedial Striatum (DMS). We found that mice, whose astrocytes in VS were targeted, showed decreased bandit performance and increased win-stay behavior. Throughout computational modeling, we showed …
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The role of frontal cortical-basal ganglia circuits in simple and sequential visuomotor learning
… to elucidate the role of frontal cortex and striatum in visuomotor learning. Several tasks were used to characterize motor function including: a visuomotor reaction time (VSRT) task, measuring response speed and accuracy to luminance cues; simple stimulus-response (S-R) learning, measuring …
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Neurochemical and Neuroanatomical Basis Of Reversal Learning In The Rat
… infusions into different regions of the striatum. Systemic raclopride had no specific effects initially on serial reversal learning, but continued treatment with a low dose did impair retention of a novel visual discrimination, and its subsequent reversal. Intracerebral infusions of …
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Region-specific Mechanisms of Estrogen and Age on Neuronal Ensemble Activity During Spatial Navigation
… on tasks that require the use of a dorsal striatum-dependent response strategy. When either strategy may be used successfully, estradiol biases females to use a place strategy. While this behavioral effect has been well-described in the young adult female rat, little is known about the …
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A Single Alcohol Pre-exposure Alters Dorsolateral Striatal AMPA Receptor Dependent Binge and Compulsive-like Drinking
… characteristic of alcohol use disorder and the dorsolateral striatum (DLS) is implicated in regulating this inflexible behavior. AMPA receptors have been implicated in both goal-directed (dorsomedial striatal dependent) and DLS dependent inflexible behaviors with antagonism in the DLS and …
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Changes in the Murine Nigrostriatal Pathway Following Pyrethroid and Organophosphate Insecticide Exposure: An Immunohistochemical Study
… re-uptake transporter protein (DAT), within the striatum of the C57BL/6 mouse, using DAT antibodies, following low (0.8, 1.5 & 3.0 mg/kg) and high (200 mg/kg) doses of PE, respectively. Possible nigrostriatal terminal degeneration was examined using antibodies to tyrosine hydroxylase (TH), the …
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Synthetic and Natural Environmental Compounds as Potential Facilitators of Mptp-Induced Parkinsonism
… effets on MPTP-induced neurotoxicity in the dorsolateral striatum of the C57BL/6 mouse, the principal target of the nigrostriatal pathway. Tyrosine hydroxylase (TH) was used as a marker for loss of dopaminergic neuropil and glial fibrillary acidic protein (GFAP) was used as a marker of glial …