Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Dopamine agonists"”.
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Two Sides of The Same Coin in The Levodopa Treatment of Parkinson's Disease
… PD is a characterized by selective loss of dopaminergic neurons in the pars compacta of the substantia nigra. Levodopa (L-dopa) and dopamine agonists have been most commonly used for symptomatic treatment. Since its initial introduction in 1967, L-dopa has been shown to be the most effective …
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IMPORTANCE OF THE D2 RECEPTOR FOR ONE- AND MULTI-TRIAL PSYCHOSTIMULANT-INDUCED BEHAVIORAL SENSITIZATION IN PREWEANLING RATS
… rats were injected with saline or the selective dopamine D2-like receptor antagonist raclopride 15 min prior to treatment with the indirect dopamine agonists cocaine or methamphetamine. Acute control groups received two injections of saline. The pretreatment regimens occurred on either PND 16 or …
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Influence of Pramipexole on Probability Discounting and Ventral Pallidal Function: Assessments in Parkinsonian-Like Rats
… with neuropathologies who are treated with dopamine agonists may be at risk to develop impulse control disorders. The overall goal of this dissertation project was to expand our knowledge on the neuropsychopharmacology of dopamine agonist-induced impulsivity. At the time this dissertation …
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Ontogeny of Prepulse Inhibition Across Sensory Systems
… with certain classes of drugs, including dopamine agonists. Because of the relative loss of PPI in inherited developmental disorders such as schizophrenia, there is great interest in understanding the developmental features of PPI (the present study) as well as its neurochemical …
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MOLECULAR MECHANISMS UNDERLYING CLINICAL BEHAVIOR OF NEUROENDOCRINE TUMORS: STUDY OF NEW POSSIBLE BIOMARKERS PREDICTABLE OF PHARMACOLOGICAL RESISTANCE AND TARGETS
… lot of attention was given to somatostatin and dopamine system, because of prevalent expression of somatostatin receptors (SSTs) and dopamine receptor type 2 (DRD2) in about all NETs that represented, over the years, the main targets for treatment with somatostatin analogs (SSAs) and dopamine …
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Gut-brain axis: Central impact of gut peptides and metabolic drug on monoamine neurotransmission
… can affect the electrical activity of dopamine neurons in the ventral tegmental area (VTA) and of pyramidal neurons in the prefrontal cortex (PFC), using single-unit activity recording techniques. We have also investigated, whether these peptides can alter some dopamine-dependent …
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Νευροφαρμακολογία και λειτουργική ανατομία των βασικών γαγγλίων του εγκεφάλου: Πειραματική μελέτη σε επίμυες
… used test for the investigation of neostriatal dopaminergic function is the rotating rat model. During the past several years however it has become apparent that the neostriatum is not an homogeneous structure. Thus in order to investigate regional differences within striatum concerning …