Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Domperidone"”.
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Improvement of Gastroparesis Management By Addressing Challenges in Drug Metabolism: Studies with Metabolite Identification, Reaction Phenotyping and In Vitro Drug-Drug Interactions
… gastric motility. Prokinetic agents such as domperidone and metoclopramide are the cornerstone in treatment of gastroparesis. Although these medications have been used for decades, essential information about their metabolism is not available. Lack of knowledge about the metabolites formed in …
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INDUCED SPAWNING OF CAPTIVE TRIPLETAIL LOBOTES SURINAMENSIS
… was very low (0.58%). Administration of Domperidone at 5 or 10 mg.kg<sup>-1</sup> in conjunction with GnRHa implants improved all metrics with best results obtained in the 10 mg.kg<sup>-1</sup> treatment-group (65.3% fertility, 2.83 spawns following induction, over 1.5 M eggs per mating …
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Controlled cultivation techniques for the recovery of threatened fishes in Virginia
… hormone releasing hormone analogue (LHRHa) and domperidone at mean dosages of 363 µg/kg and 36 mg/kg, respectively. Most females spawned within 30 h of the first injection. Stripped ova were effectively wet-spawned, and larvae hatched in 8 d at 25 C. I obtained a mean hatch rate of 55 %, but …
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HSP70 as a Target for Correction of Wilson Disease Causing ATP7B Mutants
… similarity to HSP70 inhibitors. As a result, Domperidone and glucocorticoid receptor agonists were identified and validated as effective correctors of ATP7B mutant. In summary, my findings suggest a key role for HSP70 in proteostasis of ATP7B-H1069Q and revealed FDA-approved compounds as safe …
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Exploring Gastro-oesophageal Reflux in Infants and Children
… • There is evidence of an absence of effect for Domperidone, which has associated risks in adults in terms of QT prolongation, and the prescribing of domperidone has been restricted to specialist use only. • The NICE audit tool is effective at assessing services’ ability to identify children with …
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Modification of natural hydrophilic polymers for use in pharmaceutical formulations
… chitin (0.818). Montelukast sodium and domperidone ODTs, produced using Cop-CM, displayed the required physicochemical properties. The exceptional binding, fast wetting and super-disintegration properties of Cop-CM, in comparison with commercially available co-processed ODT excipients, …