Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 93 for “"Dna microarray"”.
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Automated liquid dispensing pin for DNA microarray applications
… In particular, the application is focused on DNA microarray fabrication with the goals of smaller spot size, higher yield, more efficient usage of biological materials, and capability to handle high viscosity liquids. The new system is based on active sensing and control and it is part of a …
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Extracting transcriptional regulatory information from DNA microarray expression data
… polyhydroxyalkanoate (PHA). We have created DNA microarrays with [approximately]97% of the Synechocystis genome represented in duplicate to monitor the cellular transcriptional profile. These arrays are used in time-series experiments of differing light levels to measure dynamic …
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DNA microarray image processing based on advanced pattern recognition techniques
… segmentation methods applied to complementary DNA (cDNA) microarray images is proposed. More precise, a new gridding method based on continuous wavelet transform (CWT) was performed. Line profiles of x and y axis were calculated, resulting to 2 different signals. These signals were …
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Non-parametric algorithms for evaluating gene expression in cancer using DNA microarray technology
Microarray technology has transformed the field of cancer biology by enabling the simultaneous evaluation of tens of thousands mRNA expression levels in a single experiment. This technology has been applied to medical science in order to find gene expression markers that cluster diseased and normal …
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DNA Microarray Data Analysis and Mining: Affymetrix Software Package and In-House Complementary Packages
… and analysis represent a major challenge for microarray studies. In this study, Affymetrix software was used to analyze an HIV-infection data. The microarray analysis shows remarkably different results when using different parameters provided by the software. This highlights the fact that a …
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An analysis of the Supramolecular NanoStamping technology for its market potential based upon a review of DNA microarray intellectual property
… fabrication. The technology may be used to make DNA microarrays which are an essential tool to genomic research assisting in gene expression and genotyping. This paper explores the potential of bring Supramolecular NanoStamping technology to the microarray market. An in depth analysis of the …
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Genomweite Transkriptionsanalyse von Methanosarcina mazei Gö1
… dieser Arbeit programmiert, die es ermöglichten DNA-Microarray-Chips zu generieren, die das gesamte Transkriptom von Methanosarcina mazei Gö1 repräsentieren.Ferner wurde eine TOPO-Plasmidbank des Transkriptoms von Ms. mazei Gö1 erstellt, die es ermöglichte neue hoch spezifische PCR-Produkte zu …
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Supramolecular nano-stamping : analyzing market potential
… the science involved has market potential in the DNA microarray industry. This industry is rapidly expanding and succeeding in such an atmosphere would generate a large amount of revenue. Supramolecular Nano-Stamping provides a way to reproduce DNA microarrays at a significantly lower cost than …
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Feature selection for cancer classification using microarray gene expression data
The rapid development of DNA microarray technology enables researchers to measure the expression levels of thousands of genes simultaneously and allows biologists easily gain insight into the complex interaction in tumours on gene expression levels. Its application in cancer studies has been shown …
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SNAP Biclustering
… well in many problem domains, particularly DNA microarray analysis and collaborative filtering. A motivation for this work has been the biclustering technique known as bicACO, which was the first to use ant colony optimization. As bicACO is time intensive, much emphasis was placed on …
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Characterization of Oligonucleotide Microarray Hybridization: Microarray Fabrication by Light-Directed in situ Synthesis – Development of an Automated DNA Microarray Synthesizer, Characterization of Single Base Mismatch Discrimination and the Position-Dependent Influence of Point Defects on Oligonucleotide Duplex Binding Affinities
… oligonucleotide probes on the surface of DNA microarrays. Hybridization experiments were performed on oligonucleotide microarrays (DNA Chips) which were fabricated with an automated synthesis apparatus (developed in the framework of the present thesis). The working principle of the …
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Genom- und Transkriptionsanalyse von <i>Bacillus licheniformis</i> DSM13 - einem Organismus mit großem industriellem Potential
… DSM13/ATCC14580 wurde ein PCR basierter DNA Microarray erstellt, welcher 95% aller ORFs größer 300 bp abdeckt. Mit Hilfe der Transkriptionsanalyse konnte der Metabolismus von Bacillus licheniformis während des Wachstums mit Acetat bzw. 2,3-Butandiol als einziger Kohlenstoffquelle …
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Feature selection and classification for high-dimensional biological data under cross-validation framework
… to optimize the prediction accuracy. We utilize DNA microarray gene expression datasets to describe our methods. We have summarized our work in the following order: (1) the structure of high dimensional biological datasets and the statistical methods to analyze such data; (2) several statistical …
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Photonic Crystal Enhanced-Fluorescence and Label -Free Bioimaging
… for improved label-free imaging of immobilized DNA microarray capture spots. Applications to protein microarrays and cell-based assays are also demonstrated.
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Detection and Characterization of Multilevel Genomic Patterns
DNA microarray has become a powerful tool in genetics, molecular biology, and biomedical research. DNA microarray can be used for measuring the genotypes, structural changes, and gene expressions of human genomes. Detection and characterization of multilevel, high-throughput microarray genomic data …
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Microarray gene expression data analysis using machine learning and neural networks
<p>"As an important experimental technology, DNA microarray provides an effective way to measure the expression levels of tens of thousands of genes simultaneously under different conditions, which makes it possible to investigate the gene activities of the whole genome. However, computational …
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Genome-scale metabolic modelling of Salmonella and Lactobacillus species
… unlikely to occur in vivo. Data from Phenotype Microarray (PM), as well as DNA microarray data obtained during infection of cultured macrophage cells, was integrated with the S. Typhimurium model. The PM data was largely in agreement with model results for growth on carbon and nitrogen sources, …
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SNP auto-calling using artificial neural networks
… germane to making progress in the refinement of DNA microarray analysis and techniques regarding this issue. This study attempts to deal with the classification of microarray data and the comparison and validation of simple feedforward ANNs in partitioning high dimensional data. In doing this the …
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