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Showing 1 to 2 of 2 for “"DmPI31"”.
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A Role for PI31-Mediated Proteasome Regulation in Proteostasis and Neuronal Health
… the necessity for the proteasome regulator, DmPI31, in neuronal maintenance and show that dietary restriction and NAD+ repletion, can regulate both DmPI31 and proteasome activity. Generation of dmPI31 mutant clones in the Drosophila eye show rapid degeneration of photoreceptor cells and RNAi …
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Mechanisms of Controlled Proteolysis during Drosophila Spermatogenesis: Coordinate Action of Apoptotic Caspases and the Ubiquitin-Proteasome System
… for Nutcracker physical interactors, we isolated DmPI31. Nutcracker promotes DmPI31 stability, and a complex between these proteins is essential for both caspase activation and sperm differentiation. DmPI31 is conserved with the mammalian PI31 proteins, initially described as proteasome …