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Showing 1 to 8 of 8 for “"Disuse Atrophy"”.
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Development of a stem cell-based therapy for the recovery of skeletal muscle mass following immobilization
Skeletal muscle disuse atrophy is a debilitating medical condition that occurs as result of limb immobilization and whole body bed rest. Severe reductions to muscle mass contribute to functional declines, disability, and metabolic comorbidities, such as obesity, Type II diabetes, and cardiovascular …
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Development of a pericyte-derived extracellular vesicle therapy for the recovery of skeletal muscle mass following immobilization
… and skeletal muscle mass, a condition known as disuse atrophy. Physical therapy is standard practice following disuse atrophy and may be sufficient for complete recovery of muscle mass and function in young individuals. However, the majority of older adults are not able to fully engage in a …
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Comparative Plasma Proteomics in Muscle Atrophy Induced by Cancer Cachexia and Hindlimb Unloading
<p>Introduction: Muscle atrophy results from a dysfunction in protein turnover that leads to loss of mass and function and occurs concurrently with multiple pathologies such as cancer and extended bed rest. Atrophy reduces overall quality of life while increasing morbidity and mortality. Currently, …
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Assessment of Physiological Challenges in Overwintering Black Bears (Ursus americanus): Active Gestation, Neonatal Growth, and Skeletal Muscle Conservation
… important potential pathway for limiting muscle atrophy during bear hibernation. Understanding pre and postnatal development of ABBs is important for exploring factors related to climate, maternal characteristics, which possibly affect birthing phenology, and fitness of bears experiencing rapid …
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Development of a pericyte-based strategy to recover aged skeletal muscle after disuse
Skeletal muscle disuse atrophy is the decline of muscle mass that occurs after periods of extended bed rest or immobilization. Recovery via physical rehabilitation is often incomplete in special populations such as older adults, due to injury and pain, functional limitations, and anabolic …
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Optimization of a pericyte therapy to improve muscle recovery following hindlimb immobilization
… prevention and treatment of disability following disuse. However, one of the challenges in developing a pericyte therapy is the lack of a unique marker for identification and isolation of pericytes. Investigators have established that pericytes express a wide variety of cell surface markers, such …
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Comprehensive analysis of cellular contribution to delayed skeletal muscle recovery after disuse
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2025-05-01
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Development of an extracellular vesicle therapy to recover skeletal muscle after disuse
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-10-20 without embargo terms