Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Distal-less"”.
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Appendage development and early Distal-less regulation in arthropods: A study of the chelicerate Tetranychus urticae (Acarida)
… marked by expression of the homeobox gene Distal-less (Dll), and the focus of this thesis is to compare signalling mediated by early Dll regulatory genes activity along antero-posterior and dorso-ventral embryonic axes during limb specification in Drosophila, with the activity of their …
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UNCOVERING THE EVOLUTION AND DEVELOPMENT OF A NOVEL ABDOMINAL APPENDAGE IN BLACK SCAVENGER FLIES (SEPSIDAE: DIPTERA)
… in both species. In T. biloba, extradenticle and Distal-less are additionally co-opted while there was no evidence for the involvement of Distal-less in P. dikowi, suggesting that its role in the GRN was either lost in P.dikowi or gained in T.biloba. Surprisingly, I also demonstrate a potentially …
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A Role for the Ecdysone Response Gene E93 in Imaginaling Patterning during Metamorphosis
… pathway, and upstream of the bract target gene Distal-less, consistent with the view that E93 functions to control target gene specificity of EGFR signaling during metamorphosis. I also present the results of experiments to dissect functional domains within the E93 protein and to determine …
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The role of the wingless gene in the control of growth and pattern formation during drosophila wing development
… is the mediator of the A/P organizer, while Wingless (DWnt-l, a secreted molecule of the Wnt family) is a key mediator of the D/V organizer. In this thesis, several aspects of Wingless function in the wing imaginal disc are examined. Two regulatory mutations, spadeflag (spdfg) and Sternopleural …
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Characterisation of a conserved motif found within the Dlx cis-regulatory element URE2 and its effect on mouse URE2-lacZ activity in transgenic mice
The Distal-less-like genes, commonly referred to as Dlx genes, encode homeodomain transcription factors essential for the establishment of GABAergic interneurons in the ventral forebrain as well as their migration to the cortex. The cis-regulatory element URE2 (enhancer) is located upstream of Dlx1 …
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Regulation of growth, patterning and cell fate-specification during imaginal disc regeneration in drosophila
… from antennal fate to eye fate induced by a Distal-less-GAL4 (DllGAL4) P-element insertion that is a mutant allele of Dll and expresses GAL4 in the antennal imaginal disc. While this fate change was not induced by tissue damage, it appeared to be a hybrid of transdetermination and homeosis. …