Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"Dissolution model"”.
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An active-path-dissolution model for corrosion-fatigue cracking of drill-pipe steels in offshore drilling environments
… environments was predicted using an analytical model. This model, named the Active-Path-Dissolution (APD) model, simulates a sequence of three corrosion-fatigue processes: chemical notching process, microcrack development, and macroscopic crack growth. The first two processes are combined with …
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The Effects of Early-Age Stress on the Elastic and Viscoelastic Behavior of Cement Paste
… incorporated into a preliminary solidification-dissolution model for beam relaxation. The model, though in need of improvement through further research, shows promise in potentially predicting relaxation in cement paste and by extension, in concrete structures.
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Development of the Sustained Release Analgesic Formulations for Rodents and a Novel In Vitro Model for Parenteral Formulations with the Character of a Level A IVIVC
… desirable to develop a suitable in vitro release model for parenteral products with the characters of Level A In Vitro-In Vivo Correlation (IVIVC) and elaborate drug release mechanism. So far there is no successful in vitro dissolution method with the character of Level A IVIVC exists at present …
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Numerical Modeling of Polyvinyl Alcohol (PVA) Swelling and Dissolution in Water
This study investigates the numerical models for polymer dissolution, with a long-term goal of developing high performance dissolvable elastomer from Polyvinyl Alcohol (PVA) replacing current not dissolvable rubber based materials. With fast development of hydraulic-fracturing in past 15 years, the …
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Stochastic analysis of dense nonaqueous phase liquid dissolution in naturally heterogeneous subsurface systems
Field-scale Dense Nonaqueous Phase Liquid (DNAPL) dissolution in three-dimensional heterogeneous subsurface systems is investigated using a stochastic approach that treats the variability of flow properties as three-dimensional random fields. A steady-state, quasi-static DNAPL saturation …
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Microstructural investigation of tablet compaction and tablet pharmacological properties
… a novel parameter for characterization of tablet dissolution properties. A tablet holder was designed and used in combination with paddle dissolution test to investigate tablet dissolution process, enabling the classification of dissolution mechanisms and identification of correspondent …
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Kinetics based characterization of struvite dissolution
… objective of this work was to characterize the dissolution of field grown struvite from an Ostara Pearl reactor. Dissolution rate constants between 0.94 and 2.61 mm/min were found for field grown struvite using the shrinking object model – a surface area dependent empirical kinetics-based …
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CO₂ Capture with Lithium Oxide in Molten Salt Media : A Case Study of CO₂ Capture via Electrochemically Produced Metal Oxide
… (Li₂CO₃). Through this study, we suggested dissolution model as a crucial pathway for conversion. Lastly, we explored the effect of adding nitrite ion (NO₂⁻) to the molten salt. Irreversible side reaction between NO₂⁻ and CO₂ was confirmed with X-ray diffraction and NOₓ measurement. This …
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Modeling Dissolution in Aluminum Alloys
… during thermal treatments. Robust physical models for the kinetics of particle dissolution are necessary to predict the most efficient thermal treatment. A general dissolution model for multi-component alloys has been developed using the front-tracking method to study the dissolution of …
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Kinetics of carbide dissolution in chromium + molybdenum steels during oxidation
… the matrix was expected to trigger the carbide dissolution, and form a precipitate-free zone. Transformation of the austenitic into ferritic matrix in the precipitate-free zone was expected be essential for providing a fast chromium supply to the oxide/alloy interface. Upon exposure to pure …
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LARGE-EDDY SIMULATION OF DEEP-WATER HYDROCARBON PLUME DYNAMICS
… plume is strongly affected by the gas dissolution and hydration process that weakens the bubble-induced buoyancy for driving the plume. In this study, a new modeling strategy is developed to efficiently incorporate the gas dissolution and hydration effects into a fast Eulerian-Eulerian …
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A central Texas drying event identified at the Younger Dryas-early Holocene transition using coupled speleothem 𝛿¹³C-¹⁴C analysis
… initial ²³⁰Th/²³²Th ratio and develop an age model with better constrained uncertainties. Strong correlations between speleothem 𝛿¹³C and ¹⁴C activities can result from changes in epikarst carbonate dissolution due to variable CO2 ventilation or pore space moisture. A decrease in the …
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Nuclear Magnetic Resonance for the Characterisation of Hot-Melt Extruded Pharmaceutical Amorphous Solid Dispersions
… our understanding regarding the dynamics of drug dissolution and dispersion in viscous polymers as well as physical stability (phase separation and API recrystallization). Computational models have been built in order to predict optimal processing conditions (e.g. temperature, residence time, drug …
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Energy based dissolution simulation using smoothed particle hydrodynamic sampling
… buoyancy), but also a chemical reaction (e.g., dissolution) under the right conditions. Dissolution is one of the most common natural phenomena which is an important visual effect in fluid simulation. However this phe- nomenon is difficult to simulate due to the complexity of the behaviour and …
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Oral Drug Delivery -- Molecular Design and Transport Modeling
… validation processes involved. A computational modeling approach, which could explore the design space rapidly, reduce uncertainty and make better, faster and safer decisions, fits into the overall goal and complements the product development process. Our research focuses on the early …
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Functional organic thin films under extreme confinement
… phenomenon as well as to investigate its role on dissolution properties of APIs. Here, I observed abrupt order-to-disorder transition and stabilization of semi-crystalline and amorphous forms of three different APIs when the film thickness was decreased below a critical value of ~25-30 nm in all …