Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 432 for “"Dissection"”.
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MOLECULAR DISSECTION OF CARDIOMYOPATHY
Hypertrophic (HCM) and dilated cardiomyopathy (DCM) are inherited cardiac conditions with marked genetic heterogeneity. The genetic aetiology of HCM and DCM in Singapore and European was broadly similar but Singapore Chinese HCM patients frequently have fewer clinically actionable disease variants, …
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Functional Dissection of Brainstem Circuitry
… first part of this work describes the functional dissection of dorsal raphe cell types to elucidate their role in modulating survival functions. The second part outlines the development of a novel technology, Retro-TRAP, which we developed to address a critical, unmet need in neuroscience: …
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Dissection of Deep Neural Networks
… for computer vision. We introduce network dissection, a method for quantifying the alignment between human-interpretable visual concepts and individual neurons in a deep network. We apply network dissection to examine and compare the internal computations of several networks trained to …
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Genetic Dissection of Synaptic Vesicle Endocytosis
Synaptic transmission is mediated by the quantal release of neurotransmitters through the fusion of discrete synaptic vesicles with the presynaptic membrane. To maintain reliable transmission, synaptic vesicles and proteins must be recycled after release of neurotransmitters. A key protein in this …
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Computational dissection of nitrate transport mechanism
"Nitrogen is an essential nutrient in plants and a major driving force for crop yields and food production. Annually, about 110 million tonnes of nitrogenous fertilizers are applied globally to enhance crop yields. However, over half of the nitrogen added to the soil is lost to the environment, …
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Multiscale dissection of bacterial proteome optimization
The quantitative composition of proteomes results from biophysical and biochemical selective pressures acting under system-level resource allocation constraints. The nature and strength of these evolutionary driving forces remain obscure. Through the development of analytical tools and precision …
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Dissection of Drought Responses in Arabidopsis
… gained and a systematic molecular genetic dissection of the complex responses to abiotic stress. In this study in Arabidopsis, comparative expression profiling analysis of progressive (pDr) and moderate (mDr) drought treatments revealed common drought responses, as well as treatment …
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FUNCTIONAL DISSECTION OF ADIPOKINETIC HORMONE PRODUCING CELLS
The mechanisms of how organisms maintain metabolic homeostasis in light of significant environmental variation in food availability are not completely understood. In Drosophila, the mobilization of energy is primarily controlled by the endocrine factor Adipokinetic Hormone (AKH). AKH function is …
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Genetic Dissection of DH31 Signaling in Drosophila
Dh31, which is homologous to the mammalian Calcitonin Gene-Related Peptide, is a multifunctional neuropeptide in Drosophila. To evaluate the roles of Dh31 signaling in Drosophila, we took advantage of the KG09001 line because it has a transposable element inserted in the third intron of the Dh31 …
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Molecular dissection of Alternaria brassicicola pathogenesis mechanisms
Alternaria brassicicola is a necrotrophic fungal pathogen that causes black spot disease on cruciferous plants including economically important Brassica species and the model plant Arabidopsis thaliana. The purpose of this dissertation was to gain a better understanding of the pathogenesis …
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The nature of dissection: Exploring student conceptions
… literacy. Students who had negative reactions to dissection participated less in the activity, and demonstrated less conceptual change. Two female students showed the strongest emotional reactions to dissection, and also the lowest amount of conceptual change. One male student also had strong …
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Dissection of GnRH receptor-G protein coupling
Hypothalamic gonadotropin-releasing hormone (GnRH) (GnRH I) is the central regulator of the mammalian reproductive system. Most vertebrates studied also possess a second form of GnRH, GnRH II. GnRH I acts on its cognate G proteincoupled receptor (GPCR) on pituitary gonadotropes and activates …
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Useful Learning Tools in Anatomy Dissection Video
… exam performance and preference. METHODS. A dissection video on the carotid triangle was distributed to first year dental students in Head and Neck Anatomy. The embedded learning tools implemented in the video aimed to decrease intrinsic load and extraneous load while increasing the …
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True Anterior Hip Approach by Anatomical dissection
… hip approach Material and Methods: Cadaveric dissections were done on 51 femoral triangles of 26 cadevers. We measured length of the direct head of rectus femoris from anterior superior iliac spine (ASIS) to patella upper pole, ASIS to lateral border of femoral nerve, and entry point of …
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Dissection of CD2AP functions in epithelial cells
I have investigated a molecular mechanism that determines the shape of epithelial cells. Epithelial cells are characterized by extensive cell-cell contacts along lateral membranes that hold the cells together in cohesive sheets and by a pronounced apical-basal polarity in which the apical domain …
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Protein dissection of the Ebola virus glycoprotein
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Biology, 1998.
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Architectural Dissection and Intervention: Old Wiehle Brewery
… intervention of the new?" By using methods of dissection, one is able to deconstruct the layers of a historic situation and identify key elements of the old in an effort to provoke a dialog with elements of the new. The historic artifact, in this case an abandoned distillery warehouse, held the …
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A Molecular Dissection of the Ventromedial Hypothalamic Nucleus
… populations of VMH neurons. Laser-capture microdissection was used to isolate RNA from the VMH and from two adjacent hypothalamic nuclei known to play a role in energy balance, the arcuate (ARC) and dorsomedial hypothalamic nucleus (DMH). Amplified RNA from these three nuclei were intercompared …
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