Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Disease biomarker discovery"”.
-
Development and Application of Large-Scale Protein Folding Stability Analysis in Drug Target Identification and Disease Biomarker Discovery
… approaches in drug target identification and disease biomarker discovery. One goal of this work is to develop a novel chemo-selection strategy to improve the bottom-up proteomics readout in proteome-wide limited proteolysis experiments. Another goal of this work is to apply these methods to …
-
Discovering Biomarkers of Alzheimer's Disease by Statistical Learning Approaches
… learning approaches are exploited to discover biomarkers for Alzheimer's disease (AD). The contributions has been made in the fields of both biomarker and software driven studies. Surprising discoveries were made in the field of blood-based biomarker search. With the inclusion of existing …
-
The Development and Implementation of a TMT-SRM Assay for the Validation of Candidate Biomarkers of Alzheimer’s Disease
Biomarker discovery studies in plasma have revealed several proteins which may have clinical utility in the diagnosis and prognosis of Alzheimer’s disease. The qualification of these proteins as true biomarkers, sensitive and specific to the disease, requires rapid, high quality, quantitative …