Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 343 for “"Direct effects"”.
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Studying the direct effects of forces on embryonic stem cell behaviour
… pluripotency or differentiation. The precise effects of external forces on ES cells are confounded by forces inducing secondary changes to attachment or cell-cell signalling, which themselves can also influence cell behaviour. In this study we developed a set-up to attach cells to elastic …
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Direct Effects of Metformin On Pi3K and Ras Signaling In Endometrial Cancer
<p>Metformin has antiproliferative effects through the activation of AMPK and has gained interest as an antineoplastic agent in several cancer types, although studies in endometrial cancer (EC) are limited. The aims of this project were to evaluate pathways targeted by metformin in EC, investigate …
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The direct effects of variations in AFO stiffness on the kinematics and kinetics of gait
… on: 1. Mechanical AFO characteristics. 2. The effects of different types of AFOs on gait. Performing gait analysis and quantifying the stiffness of different orthoses could lead to more knowledge about the stiffness of AFOs and a better understanding of their effects on gait. In turn, this …
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Direct Effects of Embryos and the Uterus on the Function of Corpora Luteain Sheep and Swine
Made available in DSpace on 2014-12-09T14:29:02Z (GMT). No. of bitstreams: 1 6808184.pdf: 3995477 bytes, checksum: 0c8dc155d853b57b8e89ee46c964afdb (MD5) Previous issue date: 1967
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The direct effects of estradiol and several xenoestrogens on cell numbers of early- vs. late-stage prostate cancer cells
… to combat advanced tumors. Estrogens can indirectly decrease androgen production by central negative feedback inhibition, but may also have direct tumor killing mechanisms by a less well understood mechanism. To elucidate these mechanisms and provide understanding for potential future …
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Sunlight'S Influence On Grapevine Powdery Mildew: Direct Effects On Pathogen Development And Attendant Consequences Of Canopy Management And Vineyard Variability
… two mechanisms, i.e., UV radiation's damaging effects on the exposed conidia and thalli of the pathogen and through elevating the temperature of irradiated tissues to a level supraoptimal or inhibitory for pathogen development. Furthermore, these effects are synergistic at temperatures near the …
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An analysis of sectoral components of aggregate economic activity
This study investigated the effects of monetary and fiscal policy actions upon the real outputs of a large number of individual economic sectors. Two main hypotheses were tested: (1) monetary and fiscal policy actions have direct effects upon sectoral outputs, in addition to indirect effects …
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Does Faith-Based Worldview Predict Confidence in College Major: A Quantitative Longitudinal Study at the University of Michigan
… in community service. Results indicated direct effects from choosing a major and being involved in community service. The study also showed direct effects of choosing a major and developing a meaningful philosophy of life. The strongest finding in this study was the gap in students …
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The relationship of social support, emotional expression, and health status: a LISREL analysis of conceptual models
… Results indicated that social support had strong direct effects, but relatively weak indirect effects on health. Whereas, hostility and self-concealment were found to have indirect effects, but not direct effects, on health. Hostility affected health via effects on social support, stress, and …
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Influences on Supply Manager Behavior Toward Environmental Responsibility
… was found for all five hypotheses predicting direct effects on intention to engage in environmentally responsible behavior and actual environmentally responsible behavior. Also, direct effects for non-hypothesized relationships were found for the two moderating variables. This dissertation …
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Natural Disasters, Incidents Of Mass Violence, And Preparedness On A College Campus: A Study Of University Faculty And Staff
… For natural disasters, experience and sex had direct effects on perceived susceptibility (coefficients were a1i = .094, p = .001 for experience and a2i = .226, p = .010 for sex), but perceived susceptibility did not mediate the effect of disaster experience on preparedness behavior (b1i = .036, …
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Biological Potencies and Mechanism of Action of Estrogens and Antiestrogens in Primary Cell Cultures of Human Endometrium and in Mcf-7 Human Breast Carcinoma Cells in Vitro
… human endometrial cells were used to examine the direct effects of estrogens on progesterone receptor levels in vitro. Cells, grown in Dulbecco's EMEM, showed maximal stimulation of progesterone receptor (PR, 7-fold) after a 3-4 d incubation with 10nM estradiol (E(,2)). The
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TIME-VARYING MEDIATION EFFECTS WITH BINARY MEDIATOR IN SMOKING CESSATION STUDIES
… assessing mediation provide overall average (in)direct effects over time and omit describing the temporal characteristic of the dynamic effect. This dissertation research aims to develop a new approach to estimating time-varying causal (in)direct effects of pharmacological treatments on daily …
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The long-term role of newlywed conscientiousness and religiousness in marriage
… mechanism)? The results suggest that the direct effects of religiosity are associated more strongly with the occurrence of divorce, while the direct effects of conscientiousness are associated more strongly with the timing of divorce. Additionally, the occurrence of divorce is predicted by …
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Dehydroepiandrosterone and dehydroepiandrosterone sulphotransferase activity and expression in human disease
… Uncongugated DHEA predominately exerts its effects via its downstream conversion to active sex steroids in peripheral target tissues. In contrast the conversion of DHEAS to androgens first requires cleavage of the sulfate group, catalysed by the microsomal enzyme steroid sulfatase (STS). …
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Differential Prediction: Understanding a Tool for Detecting Rating Bias in Performance Ratings
… the differential constructs approach and the direct effects approach. One purpose of this study was to examine how the direct effects approach, and more specifically differential prediction analysis, is more useful than the other two approaches in examining the existence of rating bias. …
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Characterization of molecular and functional changes regulating hypobaric hypoxia-induced right ventricular hypertrophy
… is that in vivo Wy-14,643 admnistration elicited direct effects on mitochondrial respiratory function and cardiac contractility. The data show that Wy-14,643 treatment attenuated mitochondrial respiration (state 3 respiration and rate of ADP phosphorylation) in the RV while promoting uncoupling of …
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Adolescents' Social Capital Resources, Future Life Expectations, and Subsequent Citizenship Participation as Young Adults
… social capital had mixed results regarding their effects on the final outcome variables. Teacher interactions were not found to have a statistically significant direct effect on any of the three citizenship participation outcome variables. But this result should be viewed with caution due to …
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Spatial Dimensions of Economic Valuation: A Comparison of Hedonic Models
… add up to about 8 billion dollars if multiplier effects are taken into account in a nonlinear model. Even if only direct effects are considered, aggregate benefits sum up to 5 billion dollars.
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Ethical Leadership Development: An Examination of the Effects of Spiritual Practices and Intercultural Sensitivity
… The purpose of this study is to investigate the effects of spiritual practices on ethical leadership development and the moderating effects of intercultural sensitivity on the relationship between spiritual practice and ethical leadership. This study also aimed to examine whether the theoretical …
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