Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Direct cell reprogramming"”.
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Modelling Huntington’s Disease Using Direct Cell Reprogramming
… of generating a representative model of HD. Cell reprogramming is a revolutionary technology that can generate live, human neurons in vitro from the somatic cells of individuals with HD. Our research group was the first to demonstrate the direct reprogramming of adult human dermal fibroblasts …
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A Leap of Fate: Fluid identity, functional modules, and flexible strategies for transcription factor-based reprogramming
… that.” – Norton Juster, The Phantom Tollbooth Direct cell reprogramming is a technique used to convert a cell from one type to another, without a stable intermediate. This is commonly achieved through transcription factor (TF) over-expression in the source cell type, with TF selection based …
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Integrative genomic analysis of Neurogenin2 reprogramming of human iPSCs
Direct cell reprogramming is a rapidly growing field that has challenged traditional concepts of cellular identity. The expression of Neurogenin 2 (NGN2) results in rapid reprogramming of human pluripotent stem cells (PSCs) into functional excitatory neurons. My lab has previously demonstrated that …
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Bioartificial scaffolds with biomimetic fibrous structure in the design of in vitro models of cardiac fibrotic and skeletal muscle tissue
L'abstract è presente nell'allegato / the abstract is in the attachment