Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Dimethylhydrazones"”.
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Studies in asymmetric synthesis I the asymmetric alpha-alkylation of N,N-dimethylhydrazones II the synthesis of 1,3-amino alcohols via the aldol-Tishchenko reaction
… α-alkylated ketones employing simple non-chiral dimethylhydrazones and effecting their asymmetric alkylation using a range of chiral diamine ligands. While chiral ligands for asymmetric synthesis are not short in abundance, there are a number of structural classes renowned for their broad …
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Studies in asymmetric synthesis: I. the asymmetric α-alkylation of N,N-dimethylhydrazones II. the asymmetric aldol-Tishchenko reaction of (S)-tert-butanesulfinyl imines for the introduction of 2, 3, 4 and 5 new chiral centres in one pot
… developed within the McGlacken group using N,N-dimethylhydrazones as ketone synthetic equivalents and the chiral diamine sparteine. The first section of this thesis outlines efforts to further expand the scope of this methodology to include more diverse and challenging electrophiles. As a …
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New methods for the asymmetric synthesis of α-alkylated ketones and 1,3-amino alcohols
… approach employs the use of simple non-chiral dimethylhydrazones and their asymmetric alkylation using the chiral diamine ligands, (+)- and (-)-sparteine. The methodology described represents the first example of an asymmetric alkylation of non-chiral azaenolates. Enantiomeric ratios up to 83 : …