Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Dileucine"”.
-
The effect of leucine and dileucine ingestion on muscle protein turnover in healthy young men
… MPB rates. Plasma insulin, glucose, leucine and dileucine concentrations were also measured. Results from this study demonstrated that DILEU stimulates MPS to a greater extent than LEU. There was no difference in MPB rates between conditions. Plasma insulin, glucose, leucine, and dileucine …
-
Down-modulation of the apoptosis receptor Fas and the EGF receptor by the adenovirus E3/10.4-14.5K proteins requires the concerted action of two distinct transport signals
… the second large class of transport signals, the dileucine motifs. Both types of motifs are recognized by cellular adaptor proteins which select cargo for directed transport in clathrin-coated vesicles. FACS analysis of stable E3-transfectants expressing 10.4-14.5K mutant proteins revealed that …
-
Molecular basis of cargo sorting by endosomal trafficking machinery
… sorting of carriers. While the sorting of acidic dileucine motifs is thought to be well understood, it remains unclear how different cargoes obtained different end point localisations despite containing similar motifs. Here I resolve the interaction of a dileucine motif bound to a fragment of the …
-
Distribution and targeting of CLC-3
… binds to both clathrin and AP-2. Deletion of dileucine cluster within the cytosolic N terminal (amino acids 13-19) resulted in a molecule that had decreased endocytosis and increased surface expression. This deletion also abolished interaction with clathrin in GST pull down experiments. We …
-
Die Regulation der Expression des humanen Oncostatin-M-Rezeptors durch Januskinasen
… this signal is most likely consists of three dileucine-like signals in the interbox1/2-region. Even though one of this signals resembles a lysosomal targeting motif, no lysosomal localization of the OSMR was detected. Both immunofluorescence data and biochemcal studies rather point to an ER …
-
The mechanism of HIV-1 Nef-mediated downregulation of CD4
… was found to depend on a [D/E]xxxL[L/I]-type dileucine motif, located in the C-terminal loop of Nef, that is essential for CD4 downregulation. While mapping the binding site of AP-2 on Nef, a second determinant of interaction in the C-terminal loop was identified. Mutation of this motif, which …
-
Intracellular trafficking of Leishmania major peptidases
… carrier complex AP3, which binds to tyrosine or dileucine motifs in cargo proteins. LMP contains two such tyrosine motifs at its C-terminus, but disruption of these by site-directed mutagenesis did not affect LMP localisation, suggesting that its trafficking is AP3-independent, which is in …
-
The food matrix and its effect on human protein metabolism
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-05-11 without embargo terms