Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 37 for “"Diffusion Weighted Imaging"”.
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A numerical study of the effects of inhomogeneous media in diffusion weighted imaging
Diffusion Weighted Imaging (DWI) -a common Magnetic Resonance Imaging (MRI) technique - is used to infer material properties of tissues from the average diffusion of water molecules over brief time intervals. In particular, the Apparent Diffusion Coefficient (ADC), a measure of the magnitude of …
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Development and optimization of high resolution multi-shot magnetic resonance acquisitions for diffusion weighted imaging
Diffusion Weighted Imaging (DWI) has become a valuable tool for imaging tissue microstructure, finding use in both clinical and research settings. In order to better resolve finer structures it is desirable to acquire images with higher resolutions. Achieving higher resolutions in diffusion imaging …
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Application of diffusion weighted imaging in studying motor control and moving towards higher resolution diffusion imaging
Diffusion weighted imaging (DWI) is a magnetic resonance imaging technique that is able to give valuable insight into neuronal structure in vivo. By looking at the diffusion of water molecules, information on the integrity of different fiber pathways are able to be observed. One particular …
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Biochemistry of the uterus studied by magnetic resonance techniques
… resonance techniques, Spectral Localization by IMaging (SLIM) and Diffusion-Weighted Imaging (DWI) in studies of uterine biochemistry. The work presented strives to: (1) investigate the relation between biochemical and structural heterogeneity in normal and abnormal uterus using high resolution …
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Function follows form : how connectivity patterns govern neural responses
… functional activity in the brain. By combining diffusion-weighted imaging or DWI, with fMRI, we are able to non-invasively measure connectivity and neural responses in the same individuals and directly relate these two measures to one another. In Chapter 2, I first establish the …
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Complex muscle architecture described with diffusion weighted MRI
… causing expansion in the orthogonal direction. Diffusion weighted magnetic resonance imaging (DW-MRI), provides a convenient, non-destructive, method for deriving fiber architecture in many tissues. DW-MRI finely probes tissue microstructure by determining direction-specific variations of signal …
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EVALUATION OF INTERPOLATION AND REGISTRATION TECHNIQUES IN MAGNETIC RESONANCE IMAGE FOR ORTHOGONAL PLANE SUPER RESOLUTION RECONSTRUCTION
… aim is to use this concept on magnetic resonance imaging (MRI) data, for which the standard is to scan in several-plane orientation in a 2D fashion. As a result, clinical MRI, functional MRI (FMRI), diffusion weighted imaging (DWI)/diffusion tensor imaging (DTI), and MR angiography (MRA) tend to …
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Structure-function relationships in human brain development
… neuroanatomical connectivity, as measured with diffusion weighted imaging (DWI), can be used to calculate connectional fingerprints that are sufficient to delineate fine anatomical distinctions in the human brain (Chapter 2). Next, I describe the maturation of structural connectivity patterns by …
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Albumin Therapy in Acute Stroke Patient
… Institutes of Health Stroke Scale (NIHSS) and diffusion-weighted imaging (DWI) were serially checked. There was no adverse effect related to albumin therapy. Although there was no significant difference in both baseline NIHSS score and DWI lesion volume on admission, the NIHSS scores at the …
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Influence of Mandibular Fixed Retainers on Diagnostic Quality of Cranial MRI
… potentially undergo routine magnetic resonance imaging. Ten subjects had impressions taken and models made for retainer tray fabrication. Removable trays with each lingual retainer material incorporated in them were fabricated from the models. Subjects underwent scans with each of the five test …
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Advancing the intravoxel incoherent motion model as a tool for quantifying brain microvascular health
… blood velocity and mean microvessel length via diffusion weighted imaging (DWI). Very long mixing time stimulated acquisition mode diffusion weighted magnetic resonance imaging pulse sequences were developed and implemented to acquire the long diffusion time data required to derive the proposed …
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Spatially Selective 2D RF Inner Field of View (iFOV) Diffusion Kurtosis Imaging (DKI) of the Pediatric Spinal Cord
Magnetic resonance based diffusion imaging has been gaining more utility and clinical relevance over the past decade. Using conventional echo planar techniques it is possible to acquire and characterize water diffusion within the central nervous system (CNS); namely in the form of Diffusion …
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Nuclear magnetic resonance microscopy and diffusion
… with a home-built high resolution microscopy imaging probe. It is one of the most stable microimaging system designed and fully equipped for microscopic fMRI study. This work is an advancement of using MRI to study fundamental neuron science and cell signal pathways in vivo. NMR Microscopy of …
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Functional Imaging to enable more accurate localisation and characterisation of prostate tumours
… Therefore, the development of non-invasive imaging methods to stratify prostate cancer is important for patient management. Recently, multiparametric MRI has revolutionised the work-up of prostate cancer, becoming a routine part of clinical practice and migrating earlier in the diagnostic …
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PET-MR Imaging of Hypoxia and Vascularity in Breast Cancer
… common cancer in the UK and in women globally. Imaging methods like mammography, ultrasound (US) and magnetic resonance imaging (MRI) play an important role in the diagnosis and management of breast cancer; they are generally utilised to provide anatomical or structural description of tumours in …
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Generative models of brain connectivity for population studies
… Anatomical connectivity is measured via Diffusion Weighted Imaging (DWI), and functional connectivity is assessed using resting-state functional Magnetic Resonance Imaging (fMRI). We first develop a probabilistic model to merge information from DWI tractography and resting-state fMRI …
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Investigation of Microstructure of Uterine Fibroids in Magnetic Resonance guided High Intensity Focused Ultrasound Therapy
… therapy has several challenges: (1) The long pre-imaging time, which reduces the treatment efficiency and can cause significant patient discomfort. (2) Not all the fibroids are treatable by HIFU therapy. Current studies reported the fibroids with higher signal intensity than muscle and myometrium …
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Validation of magnetic resonance imaging (MRI) as a tool to detect inflammation in the brain
… until 4h post-treatment. MRI techniques included diffusion-weighted imaging (DWI), quantitative magnetization transfer (QMT), and magnetic resonance spectroscopic imaging (MRSI). EEGs were recorded at resting-state and during performance of an attention task. Vaccine administration induced an …
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The Role of the Basal Ganglia in Memory and Motor Inhibition
… in memory and motor inhibition. Recent neuroimaging evidence suggests a supramodal network of inhibition involving the lateral prefrontal cortex. Here we examined whether this supramodal network also includes subcortical structures, such as the basal ganglia. Despite their well-established …
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