Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"Diffusion Imaging"”.
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Cerebral white matter analysis using diffusion imaging
… whole-brain tractography segmentation problem. Diffusion magnetic resonance imaging can be used to create a representation of white matter tracts in the brain via a process called tractography. Whole brain tractography outputs thousands of trajectories that each approximate a white matter fiber …
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Magnetic resonance diffusion imaging and spectral localization: New methods and their quantitative applications
… interest, in recent years, in the measurement of diffusion of water and metabolites in living systems by magnetic resonance (MR) techniques. Knowledge of the diffusion coefficients of the molecules can yield unique information about microstructure and function of tissue. We have developed a method …
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Application of diffusion weighted imaging in studying motor control and moving towards higher resolution diffusion imaging
Diffusion weighted imaging (DWI) is a magnetic resonance imaging technique that is able to give valuable insight into neuronal structure in vivo. By looking at the diffusion of water molecules, information on the integrity of different fiber pathways are able to be observed. One particular …
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Diffusion MRI of complex tissue structure
Magnetic resonance diffusion imaging provides an exquisitely sensitive probe of tissue microstructure. Owing to the microscopic length scale of diffusion in biological tissues, diffusion imaging can reveal histological architecture irresolvable by conventional magnetic resonance imaging methods. …
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Development and optimization of high resolution multi-shot magnetic resonance acquisitions for diffusion weighted imaging
Diffusion Weighted Imaging (DWI) has become a valuable tool for imaging tissue microstructure, finding use in both clinical and research settings. In order to better resolve finer structures it is desirable to acquire images with higher resolutions. Achieving higher resolutions in diffusion imaging …
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Diffusion and Magnetization Transfer Studies of Neural Tissue
Our experiments showed that diffusion and magnetization transfer do not offer a unique window to neural function, as had been suggested by some reports in the literature. Rather, our studies taken together with the literature suggest that both these phenomena affect the standard …
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High-Resolution Diffusion Tensor Imaging and Human Brain Connectivity
<p>Diffusion tensor imaging (DTI) has emerged as a unique method to characterize brain tissue microstructure non-invasively. DTI typically provides the ability to study white matter structure with a standard voxel resolution of 8μL over imaging field-of-views of the extent of the human brain. As …
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Using simulation to estimate probability density functions of bound water molecules with DSI
… the physical basis by which high resolution diffusion imaging derives information about fiber alignment and diameter, we simulated a model diffusion experiment employing a random walk paradigm. A simulation of a model diffusion spectrum imaging experiment was written in Java in order to …
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Novel Phantoms and Post-Processing For Diffusion Spectrum Imaging
<p>High Angular Resolution Diffusion Imaging (HARDI) techniques, including Diffusion Spectrum Imaging (DSI), have been proposed to resolve crossing and other complex fiber architecture in the human brain white matter. In these methods, directional information of diffusion is inferred from the peaks …
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Numerical methods for simulating diffusion in cellular media
Diffusion imaging is a relatively recent branch of magnetic resonance imaging that produces images of human physiology through diffusion of water molecules within the body. One difficulty in calculating diffusion coefficients, particularly in the brain, is the multitude of natural barriers to water …
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Three dimensional mapping of lingual myoarchitecture
… tongue, we employed several magnetic resonance imaging techniques generally based on direction specific differences in water diffusion. Muscle tissue in particular exhibits significant diffusion anisotropy in the direction of fibers, from which diffusion imaging is able to infer fiber direction. …
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DTI and MEG Imaging of Subconcussive Impacts in High School Football Players
… on the developing brain is still unknown. Neuroimaging analysis of these players, particularly during times of brain maturation and growth, is important to profile the potential dose-response of brain changes occurring in relation to head impact exposure.
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Spatially Selective 2D RF Inner Field of View (iFOV) Diffusion Kurtosis Imaging (DKI) of the Pediatric Spinal Cord
Magnetic resonance based diffusion imaging has been gaining more utility and clinical relevance over the past decade. Using conventional echo planar techniques it is possible to acquire and characterize water diffusion within the central nervous system (CNS); namely in the form of Diffusion …
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Mapping Anisotropic Tissue Fiber and Microvasculature Architecture With Diffusion MRI: Application to Skeletal Muscle and White Matter
… in the brain. At the MR spatial encoding level, imaging techniques are developed with focus on the spatial resolution needs which depend on the anatomy and physiology of the imaged tissue. At the transport modeling level, a generalized framework is established to account for fiber and …
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The Neurocognitive Sequelae of Chronic Traumatic Brain Injury and the Utility of Treatment with Methylphenidate
… with TBI. Advances in Magnetic Resonance Imaging (MRI) technology using structural, functional, and diffusion imaging have shown utility in revealing subtle neurobiological abnormalities in patients with TBI which were previously undetectable with routine brain imaging. These have been …
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Visualisation of chemistry in flow
… of optical and magnetic resonance (MRI) imaging techniques. The coupling between reaction-diffusion and advection was studied in three distinct systems. Stationary flow-distributed oscillation (FDO) patterns, previously only observed in packed bed reactors, were produced in alternative …
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MRI techniques for quantitative and microstructure imaging
… a safe, non-invasive approach for human in vivo imaging. However, quantitative MRI typically requires the acquisition of multiple images for biophysical model fitting, which leads to long scan time that consequently causes low SNR, low spatial resolution, image artifacts and vulnerability to …
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From Structure to Function: Social and Cognitive Networks in Children Born Very Low Birth Weight
… five-year-old VLBW children. Using multi-shell diffusion imaging, studies 1 & 2 assessed white matter microstructure in VLBW compared to full-term (FT) children and associations with early nutrition (during postnatal days 9-29) and developmental outcome. Fractional anisotropy (FA), radial …
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Methods for Data Management in Multi-Centre MRI Studies and Applications to Traumatic Brain Injury
Neuroimaging studies are becoming increasingly bigger, and multi-centre collaborations to collect data under similar protocols, but different scanning sites, are now commonplace.However, with increasing sample size the complexity of databases and the entailed data management as well as …
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Diffusion Tensor Imaging (DTI) of the Pediatric Spinal Cord
Diffusion Tensor Imaging (DTI) is a technique for noninvasively examining diffusion of water molecules in each voxel of an image in directions parallel and transverse to the plane of neuronal axons. The quantitative characteristic of DTI allows for the characterization of physical properties of …
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