Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Differentiation Dynamics"”.
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Differentiation dynamics of mammary epithelial cells during normal and malignant development
… as being part of a continuous spectrum of differentiation. This view highlights the plasticity of the tissue and might help to explain some of the conflicting results from lineage tracing studies. This transcriptional catalogue of cell types in the murine mammary gland allowed us to study …
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A study into the biology of mESCs exiting naïve pluripotency and technology development for subcellular proteomics
… that have examined mESC pluripotency and early differentiation dynamics have suggested that mESCs transition towards lineage specification through a transient state of primed pluripotency that resembles that of EpiSC pluripotency. However, this hypothesis has not been methodically interrogated. …
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Deciphering the Mechanisms of Heterogeneity within Haematopoiesis in Health, Development & Disease
… that leukaemia arrested at different stages of differentiation express distinct HSC dormancy genes and differ in their prognosis, pointing towards an underexplored, yet therapeutically relevant, complexity of the stem cell state. I then integrate clonal barcoding with scRNA-seq to interrogate …