Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 250 for “"Differentially Expressed Genes"”.
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Differentially expressed genes in oesophageal cancer
… instability of clonal evolution. Several oncogenes, tumour suppressor genes and transcription factors have been shown to be altered in oesophageal cancer. Their role however, in the development and/or susceptibility to the development of oesophageal cancer is poorly understood. The aim if this …
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Identification of differentially expressed genes in breast cancer tissues and cells
… cellular characteristics, to identify genes that may be responsible for different biological behavior of these cell lines. Messenger RNA from normal, breast cancer tissues, and breast tissues from reduction mamoplasty yielded fifty-nine differentially expressed bands representing …
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A bioinformatics meta-analysis of differentially expressed genes in colorectal cancer
… have been performed, the resulting lists of differentially expressed genes tend to be inconsistent with each other, suggesting that there are some false positives and negatives. One logical solution to this problem is to determine the intersection of the lists of differentially expressed …
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Contribution to Statistical Techniques for Identifying Differentially Expressed Genes in Microarray Data
… measure the expression levels of thousands of genes (features or genomic biomarkers) simultaneously in one single experiment. Robust and accurate gene selection methods are required to identify differentially expressed genes across different samples for disease diagnosis or prognosis. The …
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Isolation and functional analysis of differentially expressed genes in human prostate cancer
Prostatakrebs ist der am häufigsten prognostizierte solide Tumor und die zweithäufigste Ursache für Krebstod bei Männern in den westlichen Ländern. Eine der Schlüsselaufgaben der Prostatakrebsforschung ist es, molekulare Marker zu entwickeln, die effektiv Progression und Malignität von …
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Identification of Differentially Expressed Genes in a Rat Unilateral Ureteral Obstruction Model
… 유전자가 UUO에서 발현이 증가 하였고, Gene for hepatocarcinogenesis-related transcription factor와 Superoxide dismutase 1, 그리고 Similar to myosin-VⅡb 3개의 유전자가 CUK에 비해 유의하게 발현이 감소했음을 확인하였다. 본 연구에서 확인된 유전자들의 발현 변화가 실존하는지에 대한 검증이 시행되어야 하며, 검증된 유전자들이 신부전에서 어떠한 역할을 할 것인지에 대한 연구가 필요할 것이다.
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Differentially expressed genes in aortic cells from atherosclerosis-resistant and atherosclerosis-susceptible pigeons
… Difference Analysis (RDA) was used to identify genes that were differentially expressed between White Carneau (WC) and Show Racer (SR) pigeon aortic smooth muscle cells. The gene(s) responsible for atherosclerotic resistance in cultured SR smooth muscle cells (SMC) were hypothesized to be silent …
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Identification of differentially expressed genes in the commercially important agarophyte, Gracilaria gracilis, following nitrogen deprivation
… the simultaneous identification of thousands of differentially expressed genes in a single assay. Combined with genomic technologies such as genetic engineering, microarray technology has the potential to identify genes that confer enhanced in vivo tolerance to a specific stress. In the current …
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Differentially expressed genes in oesophageal cancer : Retinoic acid receptor-ß2, Trio and Abl-related gene
Bibliography: leaves 95-104.
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Towards a comprehensive description of the human retinal transcriptome: identification and characterization of differentially expressed genes
… it has been difficult to estimate the number of genes actively transcribed in this tissue. Great efforts in the elucidation of retinal disease genes have led to the identification of 139 retina disease loci with 90 of the corresponding genes cloned thus far . In contrast to the success in the …
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Identification of differentially expressed genes in AHI-1-mediated leukemic transformation in cutaneous t-cell lymphoma
… identified through provirus insertional mutagenesis in murine leukemias and lymphomas. Its involvement in human leukemogenesis is demonstrated by gross perturbations in its expression in several leukemic cells lines, particularly in cutaneous T-cell lymphoma (CTCL) cell lines (Hut 78 and Hut …
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Molecular genetics of abdominal aortic aneurysm
… include inflammation, proteolysis, angiogenesis and apoptosis. It has also a strong familial predisposition with linkage studies identifying chromosomes 19q13 and 4q31 as susceptible loci. AAA is likely to be a polygenic disorder. Aims The aims of this study were to carry out a whole …
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Analysis of gene expression alterations in premalignant progression from normal mammary epithelium to ductal carcinoma in situ by multiple orthogonal tools
… GeneChip® U133A 2.0 Arrays. We found 157 genes that were consistently differentially expressed between MCF10A and different DCIS models. Pathway analysis showed that a subset of differentially expressed genes in DCIS is strongly linked to glutamate metabolism and others involved in …
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Integrative high-throughput study of arsenic hyper-accumulation in Pteris vittata
… (KOG) classification, and pathway analysis. Differentially expressed genes induced by arsenic stress were identified, which revealed several key players in arsenic hyper-accumulation. As part of the efforts to annotate differentially expressed genes, literature of plant arsenic tolerance was …
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Finding lncRNAs in bone marrow and fetal liver erythroid progenitor cells in mice
… and occurs primarily in the liver during embryogenesis and then in the bone marrow during adulthood. In spite of the different microenvironments of the liver and bone marrow, current research shows that the majority of protein-coding genes important to crythropoiesis are expressed during both …
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Contributions to Statistical Problems Related to Microarray Data
… data and use Bayes Factors to identify differentially expressed genes. Second, we study the cellular differentiation process and proposed a statistical test for detecting early differentiation genes. Third, we further proposed a model-based method for the cellular differentiation problem.
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Adaptation to environmental stress in the human placenta
… Bolivia (~400m). Among the ancestry-associated differentially expressed genes, were genes involved in inflammation and placental specific pro-angiogenic macrophages, Hofbauer cells, contributing to increased capillary growth seen among Andeans residing at high altitude. Among the …
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A Comparison of Microarray Analyses: A Mixed Models Approach Versus the Significance Analysis of Microarrays
… assessing the expression levels of thousands of genes simultaneously. Researchers hope to find genes that are differentially expressed by hybridizing cDNA from known treatment sources with various genes spotted on the microarrays. The large number of tests involved in analyzing microarrays has …
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