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Showing 1 to 20 of 396 for “"Differential expression"”.
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Differential expression of small RNAs in soybean
… are non-protein coding RNAs that regulate gene expression in plants primarily by cleaving mRNA. Two major classes of small non-coding RNAs are microRNAs (miRNAs) and short interfering RNAs (siRNAs) of 21-24 nucleotides. I selected some small RNAs that show tissue specificity based on results …
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Quantitative Approaches for Protein Differential Expression Analysis
… protocols were developed to facilitate differential protein expression analysis and biomarker discovery via a two-step sample interrogation strategy: (a) global protein profiling and differential expression analysis by spectral counting; and, (b) biomarker candidate validation by …
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Differential Expression of Cell Adhesion Molecules by Neuronal Injury
… to injury. Therefore we are thought to that the expression of these CAMs is associated with neurodegenerative disease by neuronal injury. In this study, we investigated the expression of CAMs is changed by neuronal injury and what types of CAMs are expressed in glial cells and neurons. We used a …
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Differential expression of microRNAs in human External Cervical Root Resorption
… This study aims to quantify the level of expression of miRNAs in ECR to target lesion progression, using arrays for over 1,000 miRNAs Sample tissue of external cervical resorption (ECR), periapical radiolucent lesions (PARL) and periodontal ligament (PDL) was collected from 129 teeth of 62 …
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The sixth-order Krall differential expression and self-adjoint operators.
… GNK Theory for symmetric, or symmatrizable, differential expressions in L2((a, b);w). Then we review how this theory was applied to find a self-adjoint operator in L2 \mu(-1, 1) generated by the sixth-order Lagrangian symmetric Krall differential equation, as done by S. M. Loveland. We later …
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Comparative analysis of parametric, nonparametric and permutation methods for differential expression
DNA microarrays permit us to study the expression of thousands of genes simultaneously. They are now used in many different contexts to compare mRNA levels between two or more samples of cells. Microarray experiments typically give us expression measurements on a large number of genes. Increasing …
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Comparison of different differential expression analysis tools for rna-seq data
… in different subject groups. A lot of differential expression analysis tools for RNA-seq have been developed, but there is no golden standard in this field. In this research, four commonly used tools (DESeq, edgeR, limma, and cuffdiff) are studied by comparing their performances in the …
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Differential expression of beta 2 integrins in Korean Behcet’s disease patients
… possible relationship between beta 2 integrins expression and BD. Materials and methods: BD patients (n=51) consisting of 22 active patients and 29 inactive patients, 20 recurrent aphthous ulcer (RAU) patients and 23 healthy controls (HC) were included. The expression of CD11a, CD11b, CD11c, as …
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Differential expression and phenotypic activities of osterix in equine mesenchymal stem cell populations
… and OSX transcript levels, and 2) increasing OSX expression in ADI-MSCs improves their osteogenic capacity. The third series of experiments evaluated the comparative BMP signaling activities in ADI- and BM-MSCs to determine whether 1) osteogenic BMP ligand expression differs, 2) BMP inhibition in …
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Differential Expression of Genes During Diapause in the Flesh Fly, <em>Sarcophaga crassipalpis</em>.
… of this study was to identify genes that are differentially regulated during diapause when compared with nondiapausing pupae in <em>Sarcophaga crassipalpis</em>. The results of a Suppression Subtractive Hybridization procedure was used to indentify genes that are differentially regulated in …
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A Tail-Based Test For Differential Expression Analysis and Pathway Analysis In Rna-Sequencing Data
… tests based on the mean or median difference for differential expression likely suffer from low power when the between-group difference occurs mostly in the upper or lower tail of the distribution of gene expression. We propose a tail-based test to make comparisons between groups in terms of a …
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Systematic analysis of the role of differential expression of microRNAs associated with cell death decisions
The link between abnormal microRNA expression and cancer has been widely reported. However, little is known about the relationships between temporal microRNA expression and changes in cell behavior. To better understand how microRNA expression is involved in cell responses it is necessary to know …
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Differential expression profiling of proteomes of pathogenic and commensal strains of Staphylococcus aureus using SILAC
… pathogen. We proposed the variation in protein expression by commensal and pathogenic strain as an important factor behind the difference in pathogenicity. The identification of differentially expressed proteins was carried out using a quantitative mass spectrometry (MS)-based proteomic …
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Beyond differential expression : methods and tools for mining the transcriptomic landscape of human tissue and disease
… becomes an arduous task. Furthermore, prior gene expression analyses, both large and small, have been dichotomous in nature, in which phenotypes are compared using clearly defined controls. Such approaches may require arbitrary decisions about what are considered "normal" phenotypes, and what each …
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Differential Expression Of Proteins Involved In VLDL Trafficking Causes Reduced VLDL Secretion In Male Ames Dwarf Mice
… is reduced in Ames dwarf mice because of reduced expression of proteins regulating VLDL and VTV formation. To test our hypothesis, we first performed VTV-budding assay using cellular fractions isolated separately from Ames dwarf (df/df) and wild-type (N) mice livers. Our results show a significant …
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Differential Expression Analysis of Type II Toxin-Antitoxin Genes of Pseudomonas aeruginosa PAO1 under Different Environmental Conditions
… ubiquitous presence, no studies have shown the differential expression pattern of its toxin-antitoxins, and persistence related genes. The purpose of the following study is to analyze differential expression of P. aeruginosa PAO1 type II toxin-antitoxins and persistence related genes under …
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Differential expression of proteins involved in sEV biogenesis and secretion in Parkinson’s disease and Dementia with Lewy bodies
Exosomes, small extracellular vesicles (sEVs), play a pivotal role in cell-to-cell communication, carrying diverse biomolecules such as proteins, lipids, and nucleic acids. Their ability to transport these molecules makes them fundamental to various physiological processes and valuable in …
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Determining the role of differential expression of candidate icroRNAs in cardiometabolic diseases among South African adults living with HIV
… risk factors. In this study the association of differential expression of candidate miRNAs, miR-126-3p, -223-3p, and -320a with CMDs was investigated among PLWH. Methods: Using a cross-sectional study design ≥18-year-old PLWH were recruited from 17 random HIV clinics in the Western Cape, South …
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