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Showing 1 to 20 of 26 for “"Diethylstilbestrol"”.
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The mechanism of T cell dysfunction induced by Diethylstilbestrol
… have the ability to alter the immune system. Diethylstilbestrol (DES), asynthetic estrogen, is known to have estrogenic activity and induce thymic alterations.We investigated the mechanism by which DES is able to alter T cells and thus theimmune system. First, we studied the effect of DES on …
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The effects of diethylstilbestrol on myometrial contractility in mice
<p>"Diethylstilbestrol (DES) is a synthetic estrogen used in the United States from 1938-1971 for the prevention of preterm birth. It has been shown to cause structural changes to the myometrium of mice and humans, as well as gross anatomical malformations, adenocarcinoma, and infertility in both …
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The Metabolism of Tritium-Labeled Diethylstilbestrol Fed to Steers
Made available in DSpace on 2014-12-05T17:47:32Z (GMT). No. of bitstreams: 1 0019852.pdf: 2628009 bytes, checksum: a2b99a6ce58cd61a298a13c14ecf4020 (MD5) Previous issue date: 1956
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Immunomodulatory Effects of Diethylstilbestrol During Prenatal and Adult Life
For nearly forty years diethylstilbestrol (DES) was administered to pregnant women to maintain healthy pregnancies. During this time, it is estimated that several million men and women have been exposed to DES during sometime of their life. The most common period of exposure was during fetal …
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Spectrokinetic studies of the photostability and the photodegradation of Diethylstilbestrol
… and photostability of the photoactive Diethylstilbestrol compound (DES) a synthetic oestrogen sometimes used in the treatment of specific cancers. Both photochemical and photostability studies were carried out in order to contribute new knowledge to the research on DES. Due to the …
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Effects of Diethylstilbestrol on Reproduction in the Black-Tailed Prairie Dog
… ludovicianus) and to test effectiveness of diethylstilbestrol as a reproductive inhibitor. Embryo body lengths from 10 pregnant females were compared to body lengths of 14 known day-old young to learn the peak breeding period when an estrogenic chemosterilant would be most effective. …
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Studies on the Metabolism and Physiological Action of Diethylstilbestrol in Ruminants
Made available in DSpace on 2014-12-05T17:47:38Z (GMT). No. of bitstreams: 1 6000193.pdf: 6123162 bytes, checksum: f4943c90ab89678942778f3b2463cd01 (MD5) Previous issue date: 1959
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Lipogenesis in the Ruminant and the Influence of Diethylstilbestrol on Adipose Tissue Metabolism
Made available in DSpace on 2014-12-10T22:30:23Z (GMT). No. of bitstreams: 1 7212225.pdf: 3450549 bytes, checksum: 4ce2a4afddf3572a2782e7d050d46f60 (MD5) Previous issue date: 1971
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Diethylstilbestrol Nanosuspensions for Prostate Cancer: Subcutaneous Sustained Release Formulations and Pre-clinical PK/PD Evaluations
… prostate cancer have been estimated for 2013. Diethylstilbestrol (DES) was mainstay treatment for metastatic and castrate resistant prostate cancer for half a century. In the mid-1980s its use was drastically reduced because of its severe cardiovascular toxicity and thromboembolic complications …
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The Metabolic and Growth Stimulatory Effects of Diethylstilbestrol and Its Relationship to Growth Hormone in Lambs
Made available in DSpace on 2014-12-09T14:29:04Z (GMT). No. of bitstreams: 1 6915291.pdf: 3440397 bytes, checksum: 5e85036004526d6815bfcab8a4183389 (MD5) Previous issue date: 1969
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Effects of Diethylstilbestrol on Murine Early Embryonic Stem Cell Differentiation Using an Embryoid Body Culture System
… formation and function are well documented. Diethylstilbestrol (DES), a synthetic estrogen, has been linked to neoplasia and immune cell dysfunction in humans and animals exposed in-utero. In-vitro effects of DES exposure of murine embryonic stem (ES) cells on the early embryonic immune …
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Evaluation of a technique employing the chemosterilant diethylstilbestrol for suppressing reproduction of wild foxes in Virginia
A field test using diethylstilbestrol was conducted on the 13,000-acre Havens area on Fort Lewis Mountain, Roanoke County, Virginia; reference areas were also selected. Foxes were pre-conditioned to bait acceptance using molded beef suet. A total of 614 suet baits each containing diethylstilbestrol …
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Immunotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and Diethylstilbestrol (DES) in the Fetal Mouse Thymus and Liver
Diethylstilbestrol (DES) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) have been identified as immunotoxicants causing thymic atrophy, thymocyte hypocellularity, phenotypic changes detected by CD4 and CD8 surface antigens, and progenitor T-cell targeting in the fetal mouse. We hypothesized that …
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The effects of diethylstilbestrol on pelvic area, percent calf crop, calving difficulty and body size relationships in Hereford heifers
Call number: LD2668 .T4 1968 H344
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SYNTHESES AND ESTROGENICITY STUDY OF DIETHYLSTILBESTROL AND BISPHENOL-A ANALOGS AS POTENTIAL REPLACEMENT FOR BISPHENOL-A AND INVESTIGATION ON NOVEL REACTIONS INDUCED BY IODANE/QUATERNARY AMMONIUM HALIDES
Dynamic isomerization of diethylstilbestrol (DES) makes it difficult to ascertain the active estrogen between its E and Z isomers. An indirect approach has been used in this project to identify the active estrogen. Methoxylated E- and Z-DES (13 and 14) and 9,10-diethylphenanthrene-3,6-diol (15), a …
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Characterization, purification, and DNA sequence analysis of a novel ATPase of the archaebacterium Methanococcus voltae
… The enzyme activity was also inhibited by diethylstilbestrol. However, it was insensitive to N,N$\sp\prime$-dicyclohexylcarbodiimide, bafilomycin A$\sb1$, nitrate, ouabain and oligomycin. The enzyme displayed a high preference for ATP as substrate, was dependent on Mg$\sp{2+}$, and had a pH …
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The Use of Delayed Implantation Model in The Study of Hormonal Requirement for Implantation in The Rat
… g BW) resulted in fewer implantation. Similarly, diethylstilbestrol induced implantation when given at doses of 0.5 and 1.0 (mu)g/200 g BW. The more effective dose, 0.5 (mu)g/200 g BW resulted in only 50% of rats implanted.
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A new pathway in the induction of breast cancer
… mRNA and protein expression were induced by both diethylstilbestrol and 17ß-estradiol in ER!-positive MCF-7 cells. Close analysis of the PBF promoter showed that the region -399 to -291 relative to the translational start site contains variable repeats of an 18bp sequence housing a putative ERE …
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Development of Techniques for Distribution of Baits To Raccoon for Chemosterilant Studies
… an animal sterile the next breeding season. Diethylstilbestrol (DES), which is effective only during the breeding season, was field tested. Female raccoons were collected and maximum uterine swellings for each embryo in the uterus were measured to determine embryo age and date of conception. …
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