Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Dietary polyphenols"”.
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Influence of dietary polyphenols on carbohydrate intestinal digestion and absorption
… beverage. While grape juices remain a major dietary source of phenolics, they are also well recognized to be naturally high in sugar content. Insights into the ability of natural fruit phenolics to modify glycemic response of grape juice were investigated <em>in vitro. </em>Also, in …
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Bone-Specific Metabolism and Mechanism of Action of Curcuminoids in Blocking Osteolysis in Breast Cancer and Other Resorptive Bone Diseases
… bone resorption. Curcuminoids, dietary polyphenols derived from the turmeric rhizome, inhibit progression of osteolytic bone metastases and other resorptive diseases by targeting osteoclasts and – in the case of bone metastases, also blocking tumoral TGFβ signaling – despite …
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SYNTHESIS AND CHARACTERIZATION OF RESVERATROL AND ITS CONJUGATED METABOLITES AND CONTRIBUTION OF METABOLISM TO ITS DECREASED BIOVAILABILITY
… and chemotherapeutic properties of the dietary phytochemical resveratrol continue to undergo active investigations. Systemic pharmacokinetics of this compound revealed that it was rapidly and extensively metabolized into its sulfate and glucuronide conjugates. This extensive metabolism …
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Polyphenols and Their Effect on Health and Performance in Active Individuals
… based on injudicious scientific research. Polyphenols appear to be effective antioxidants, anti-inflammatory, antiviral and immune-modulating agents, however the degree to which the numerous in vitro studies translate to clinically meaningful human outcomes is undetermined. Currently …
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The Cellular and Molecular Properties of Flavinoids in Prostate Cancer Chemoprevention
Flavonoids are a large class of dietary polyphenols that have emerged as candidate agents for chemoprevention in prostate cancer. Despite the large number of known flavonoids (over 9000), only a few have been studied in prostate cancer to date. The work presented in this thesis describes the …
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Engineering of polyphenol metabolism in tomatoes to enhance anti-cancer activities
… using a metabolic engineering approach. Dietary consumption of plant secondary metabolites such as anthocyanins and other polyphenols are linked to a reduced risk of developing chronic, non-communicable diseases such as cancer, type 2 diabetes and cardiovascular diseases. High-anthocyanin …
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Metabolism in Vascular Endothelial Cells: Effects of Hyperglycaemia, Pro-Inflammatory Cytokines and Polyphenols
Hypothesis: Dietary polyphenols can overcome the deleterious effects of hyperglycaemic or inflammatory conditions on the vascular endothelium by modulating endothelial cell metabolism. Results: First, the effects of high-glucose concentrations, inflammatory cytokines and polyphenols on markers of …
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VALORIZATION OF CHESTNUT BY-PRODUCT FOR GASTROINTESTINAL HEALTH
… viability and inflammation in gastric cells. Dietary polyphenols, including tannins, have been reported to interfere with key targets of inflammation, including the nuclear factor κB (NF-κB). A promising role as a further therapeutical target for gut disorders has been recently proposed for …
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The effects of quercetin on iron metabolism
Polyphenols are known to be major inhibitors of dietary non-haem iron bioavailability, mainly through their action as iron chelators. In this present study Caco-2 cells were used to investigate the influence of quercetin, the most abundant flavonol in the diet, on non-haem iron bioavailability …
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Role and mechanism of action of the anthocyanin, delphinidin, in protecting endothelial cells against oxidative stress
Diet-derived polyphenols are believed to have health benefits on account of their antioxidant properties. Cardiovascular health is considered to be a suitable target for antioxidant therapy because oxidative stress is implicit in atherogenesis – the disease process that underpins heart attacks, …
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The Influence of Dietary Flavanol Mean Degrees of Polymerization on Sensory Preference Trends and the Metabolic Syndrome
… and taste perception has been well documented. Dietary flavanols are secondary plant metabolites that exist naturally in a wide array of polymerization states. The mechanisms behind the protective effects of flavanols are not entirely understood, particularly when considering how the mean …
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Effetto pro-ossidante e pro-infiammatorio degli ossisteroli in cellule intestinali: attività modulatoria della frazione fenolica del vino
… endogenous antioxidant defenses. Among dietary-derived antioxidants, phenolic compounds have been described to have a wide range of biological activities and many reports have illustrated their promising role as preventive tools in several acute and chronic disorders. Phenolic compounds …