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Showing 1 to 1 of 1 for “"Didox"”.
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Mechanism of tamoxifen resistance in breast cancer
… cells with the small molecule RRM2 inhibitor Didox significantly reduced cell growth in vitro and in vivo. To further establish a functional association between RRM2 expression and tamoxifen resistance in breast cancer cells, gain of function studies were performed by overexpressing RRM2 in …