Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Dickkopf 1"”.
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Regulation of Dkk1, an Inhibitor of the Wnt Signaling Pathway, by DAX-1 in Mouse Embryonic Stem Cells
… through PCR array methodology (Torres 2013). The Dickkopf 1 gene (Dkk1) was identified as a potential target of DAX-1 by these studies and has since been confirmed to be a DAX-1 target in mESC. However, to date very little is understood of the mechanism of DAX-1 repression of Dkk1 in mESC. In …
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The Effects of a Single Bout of Plyometric Exercise on Anabolic and Catabolic Osteokines in Girls and Adolescents
… anabolic Wnt signalling pathway [sclerostin and dickkopf 1 (DKK-1)] and the catabolic RANKL pathway, [osteoprotogerin (OPG), receptor activator of nuclear factor kappa-β ligand (RANKL)], as well as the related transforming growth factors (TGF-β1, TGF-β2 and TGF-β3) to an acute bout of plyometric …
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Targeting Kremen1 Downregulation with RVG-9R/siRNA Complexes in the Triple-Transgenic Mouse Model of Alzheimer’s Disease
… of the canonical Wnt signaling pathway by Dickkopf-1 (Dkk-1). Under normal conditions, the canonical Wnt signaling pathway is responsible for normal neuronal development, synaptic plasticity, and overall normal brain function. Amyloid-[beta] (A[beta]) plaques and neurofibrillary tangles are …
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New insights into cornea-lens regeneration in Xenopus laevis: the role of Wnt/beta-catenin signaling and the regenerative capacity of the limbal region
… molecule IWR-1, treatment with recombinant human Dickkopf-1 (rhDKK1) protein, or transgenic expression of Xenopus DKK1, did not significantly affect the percentage of successful regeneration. Together, these results suggest a model where Wnt/β-catenin signaling is active in the larval cornea …