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Showing 1 to 2 of 2 for “"Diastereoselective α-alkylation"”.

  1. Diastereoselective α-Alkylation of Chiral β-Borylated Esters

    … This thesis reports the development of a novel diastereoselective reaction for the α-alkylation of chiral β-borylated esters. We propose that standard deprotonation of chiral β-borylated esters with lithium diisopropylamide (LDA) leads to the formation of a boron"ate" intermediate that upon …

    vt Repository record for Diastereoselective α-Alkylation of Chiral β-Borylated Esters (opens in a new tab)

  2. 1. C-C Bond Formation via Soft Enolization and Umpolung-like Chemistry 2. Electrophilic Fluorination of Organozinc Reagents

    … β-silylated azoalkenes intermediate towards anti-diastereoselective α-alkylation of ketones. In addition, we explored a streamlined approach towards monofluorohydrocarbon formation via electrophilic fluorination of organozinc compounds. We hope this will have wide applicational utility as C-F …

    houston Repository record for 1. C-C Bond Formation via Soft Enolization and Umpolung-like Chemistry 2. Electrophilic Fluorination of Organozinc Reagents (opens in a new tab)