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Showing 1 to 1 of 1 for “"Diacylglycerol kinase alpha"”.

  1. Therapeutic targeting of DGKA-mediated macropinocytosis in lymphangioleiomyomatosis

    … drug library. We identified that ritanserin, a diacylglycerol kinase alpha (DGKA) inhibitor, synergizes with Chloroquine (CQ) to selectively inhibit proliferation of TSC2-deficient mouse embryonic fibroblasts (MEFs) compared to TSC2+/+ MEFs. OBJECTIVE: We hypothesized that TSC2-deficient cells …

    bu Repository record for Therapeutic targeting of DGKA-mediated macropinocytosis in lymphangioleiomyomatosis (opens in a new tab)