Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 24 for “"Diabetic neuropathy"”.
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Risk assessment tool for diabetic neuropathy.
Peripheral neuropathy is one of the serious complications of diabetes. Symptoms such as tingling and loss of touch sensation are commonly associated with the early stages of neuropathy causing numbness in the feet. Early detection of this condition is necessary in order to prevent the progression …
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Prevalence and treatment of painful diabetic neuropathy
… complications are also rising. Painful diabetic neuropathy (PDN) is a well-known complication of diabetes and the most common cause of all neuropathic pain. About one-third of all diabetes patients suffer from PDN. The reported prevalence of PDN varies from 11% in Rochester, Minnesota, …
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Taurine depletion and Schwann cell dysfunction in diabetic neuropathy
… UK suffer from diabetes, 50% of whom suffer from diabetic neuropathy. Patients with diabetes have low levels of platelet and plasma taurine and in animal models taurine supplementation ameliorates neuropathic symptoms. The mechanisms behind Taurine depletion and taurine supplementation are not …
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The patient's experience of painful diabetic neuropathy : an empirical study
This study explores the experience of painful diabetic neuropathy (PDN).Although PDN has a prevalence of a third of the general diabetes population it isoften an ill considered problem. It has a poor level of recognition from themedical establishment and from the general population. The devastating …
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Neuronal Toxicity of Humoral Factors From Patients With Diabetic Neuropathy and Mechanism of Neuronal Death on Cultured Adrenergic Neurons: Studies of Autoimmune Pathogenesis in Diabetic Neuropathy
<p>Diabetic neuropathy is an extremely common medical problem because of the high frequency of diabetes and its complications. Diabetic neuropathy consists of not one, but many patterns of nerve injury, each potentially with its own discrete pathogenic mechanisms. Evidence is accumulating that …
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Neuroprotective Potential of a Lanosteryl Triterpene from Protorhus longifolia Stem Bark (Benrh.) Engl in high fat diet fed and STZ -induced diabetic neuropathy in rats
Chronic hyperglycemia, observed in the diabetic state, is responsible for various diabetes related complications including development of diabetic nephropathy. Diabetic neuropathy development and progression is linked to various hyperglycemia-induced cellular and tissue damaging factors such as …
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Medicinal cannabis for neuropathic pain
… with about half of those diagnosed developing diabetic neuropathy. Other causes are genetic diseases (e.g. Charcot-Marie-Tooth disease), immune disorders or medications (e.g. chemotherapy drugs) or injury. Neuropathic pain, regardless of its cause, is often poorly managed leading to poor …
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The Prediction Model of Disease Progression of Micro and Macro-complication in Diabetes Mellitus
… complication model is as follows : First, diabetic retinopathy model was defined as no retinopathy, nonprofilerative retinopathy, profilerative retinopathy, macular edema, and blindness. Second, diabetic nephropathy model was defined as microalbuminuria, clinical nephropathy, end-stage …
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Voluntary Exercise and Neurotrophin Signaling Affect the Development and Presentation of Painful Neuropathy
Diabetic neuropathy (DN) is the most common and debilitating complication of type 1 and type 2 diabetes with approximately half of all patients developing neuropathy during the course of their lives. Additionally, patients with prediabetes also develop neuropathy, often presenting with painful …
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Glucose-Induced Apoptosis of Schwann Cells In vitro
… responsible for the pathologies associated with diabetic neuropathy. As diabetes causes increased extracellular glucose levels, glycosylation or non-enzymatic glycation of cell surface receptors may interfere with normal signaling between axons and Schwann cells and trigger the apoptotic pathway …
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Peripheral neuropathy in hypertension
… and may show evidence of subclinical peripheral neuropathy. Hypertension is strongly associated with diabetic neuropathy and the observed sensory loss may be aggravated by hypertension-induced nerve ischaemia and hypoxia. Two studies are presented in this thesis. First, 20 hypertensives and 25 …
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Neurosteroids: endogenous analgesics?
… of diabetes. Spinal dorsal horn neurones of diabetic rats exhibit abnormally high spontaneous firing, suggesting an imbalance between excitatory and inhibitory signals converging within this structure. GABAergic neurones within the spinal cord and thalamus are crucial for the transmission of …
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Combinational Therapy to Mitigate α-Dicarbonyl Toxicity
… complications. Secondary complications include diabetic neuropathy, nephropathy and cardiomyopathy. A recently discovered TRPA-1-Nrf-2 pathway is a conserved mechanism in vertebrates and invertebrates that detoxifies α-DCs; however, regulators that activate the detoxification mechanism are …
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Estudo dos potenciais evocados auditivos de curta latência em pacientes diabéticos do tipo 2 sem sintomas auditivos
… since 1857, when Jordão reported a case of diabetic patient with auditory impairment. The incidence of subclinical central diabetic neuropathy is unclear due to difficulty in detecting latent alterations of central neural transmission process. Objective: The aim of this study is to evaluate …
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The Effect of Subthreshold Vibration on Lateral Reactive Balance
… young adults, older adults, and persons with diabetic neuropathy). However, there is limited literature examining whether these effects extend to reactive balance contexts. Therefore, the primary purpose of this study was aimed at determining whether vibratory noise input changes postural …
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Characterization of Palmitic Acid Induced Lipotoxicity in Schwann Cells
… to ameliorate debilitating conditions such as diabetic neuropathy.</p>
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The Role of Advanced Glycation End Products (AGEs) through the TRPA-1/NRF-2 Activation Pathway in the Neurodegenerative Diseases
… with various age-related diseases including diabetic complications and neurodegenerative diseases. Aging and long-term hyperglycemia causes enhanced production of this highly reactive α-dicarbonyl, which reacts with macromolecules causing irreversible damage of DNA and protein promoting the …
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Relating Heart Rate Variability, Urinary Catecholamines, and Baseline Fitness to Respiratory Distress Index and Severity of Disease in Obstructive Sleep Apnea Patients
… suffering from coronary heart disease or diabetic neuropathy. Research has shown that patients with Obstructive Sleep Apnea (OSA) also show a decrease in HRV, as well as an increase in sympathetic drive characterized by an increase in the low-frequency component of HRV. HRV, in conjunction …
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Συσχέτιση επιπέδων λιποπρωτείνης (α) με τις μικροαγγειακές επιπλοκές του σακχαρώδη διαβήτη τύπου 2
… “lipoprotein(a)”, “hypolipidemic therapy diabetic microvascular complications”, “diabetic nephropathy”, “diabetic retinopathy” και “diabetic neuropathy”. Η αρχική αναζήτηση ανέδειξε 4.856 άρθρα. Μετά την αφαίρεση των διπλοτύπων και την αξιολόγηση τίτλων και περιλήψεων, 286 μελέτες κρίθηκαν …
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