Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"Diabetic foot ulcers"”.
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Predicting Outcomes in Patients with Diabetic Foot Ulcers
… factors of key outcomes and management of diabetic patients with foot ulcers. In Chapter 1 we present a broad review of the topic emphasising the pathophysiology and principles of management of the diabetic foot. It has been published as a chapter of the book “Mechanisms of Vascular …
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Novel antimicrobial combinations for treatment against pathogens associated with infected diabetic foot ulcers
Many promising conventional antimicrobial agents have low permeability and restricted biodistribution, their encapsulation into efficient drug delivery carriers is crucial to increasing their bioavailability and retention time. Lipodisq® (LQ) nanoparticles consist of a circular phospholipid bilayer …
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Evaluating the Initial Management and Referral Process for Patients with Diabetic Foot Ulcers
… of the U.S. population is living with diabetes. Diabetic foot ulcers (DFU) are one of the most prevalent and debilitating complications. One in four people with diabetes will develop a DFU at some point in their lifetime. The consequences of non-healing DFUs include risk of amputation, further …
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Genetically Engineered Wound Dressing for Sensing and Treating Candida albicans Infections in Diabetic Foot Ulcers
A quarter of diabetics suffer from diabetic foot ulcers due to chronic nerve damage, a leading complication found in many patients. Symptoms cause changes in the skin's environment, leading to frequent cuts in the skin. This often results in recurrent foot ulcers that are at high risk of …
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Developing a single dressing containing both antifungal and antibacterial drugs for treating mixed infections in diabetic foot ulcers
The prevalence of chronic wounds such as diabetic foot ulcers (DFUs) is growing at an epidemic rate in the United Kingdom, with a high cost burden for the National Health Service and are prone to infections. Mixed bacterial-fungal infections are more complicated than single microbe infections with …
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Der Einfluss von Matrix-Metalloproteinasen und ihrer Inhibitoren auf die Entstehung chronischer Wunden
… wound fluids derive from 45 patients with diabetic foot ulcers, pressure and venous ulcers which were compared to 15 fluids of acute wounds collected form patients on day 2 after split thickness skin grafting. Chronic non healing ulcers were characterized by significantly higher levels of …
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The microbiology of diabetic foot infections: a Ghanaian perspective
Diabetic foot ulcer (DFU), a major complication of both types 1 and 2 diabetes, develops in about 15–25% of people living with the disease. In Ghana, DFUs contribute to most hospital admissions (53%) among diabetics with high rates of amputation (33.3%) and death (8.8%). Diabetic foot ulcers are …
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Early-Detection of Diabetic Foot Ulceration using Thermal Images
… author's research into the early detection of diabetic foot ulceration using infrared imaging. This project may contribute to better treatment and potentially help to avoid a significant amount of amputations and deaths. An experimental infrared system was developed and successfully tested …
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The Effects of Diabetic Foot Care Education on Assessments and Behaviors among Adults with Diabetes Mellitus Experiencing Homelessness
… homelessness are at risk for preventable diabetic foot complications, including diabetic foot ulcers and non-traumatic lower extremity amputation. Several risk factors such as the lack of routine healthcare, insurance, nutritious meals, and access to diabetic foot self-care education, …
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Design and development of a smart, self-contained, portable negative pressure wound therapy device
… wounds. Costs of chronic wounds such as diabetic foot ulcers are estimated to be $25 billion, with 6.5 million patients being affected. Improving the portability and efficacy of NPWT devices will allow a larger migration of patients from hospital stays to at-home care. Current portable …
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Analysis and Design of a Feedback Controlled Adaptive Pneumatic Cast
… designed. The cast is intended to aid healing of diabetic foot ulcers by relieving pressure from the sole of a patient's foot and distributing it to the calf. This is accomplished by a pneumatic system which maintains set pressure in multiple air bladders. The research began by defining an …
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The Impact of Race on Plantar Loading and Research Engagement
… Americans (WA) to experience diabetes-related foot amputation due to foot ulcers. Foot ulcers are often caused by high plantar pressure, and several factors can impact plantar loading. Thus, there is a need to determine if race is a significant predictor of plantar loading. Additionally, with …
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Redesigning diabetic foot risk assessment for amputation prevention in low-resource settings: Development of a purely mechanical plantar pressure evaluation device
As global diabetes rates skyrocket, diabetic foot complications constitute a massive and rapidly growing global health problem, causing one million lower-extremity amputations every year. These amputations are typically preceded by largely preventable diabetic foot ulcers (DFUs). However, 80% of …
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Insights into the mechanisms of wound repair and the role of TP508 in tissue regeneration
… has been shown to accelerate healing in human diabetic foot ulcers, these studies used two models of impaired wound healing to investigate the role of TP508 in dermal wound healing. These studies found that TP508 promoted wound healing in mouse models of radiation combined with injury (RCI) and …
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Laser-processed parchment paper for fabrication of chronic wound dressings with selective oxygenation
<p>Chronic non-healing wounds (e.g., diabetic foot ulcers and bed sores) impact over 6.5 million Americans per year, costs in excess of $25 billion to treat on an annual basis, and are on the rise due to increasing levels of obesity and diabetes compounded by an aging population. A major inhibitor …
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Diabetic foot: microbiology, pathogenesis and glycan studies
… of morbidity and mortality around the world. Diabetic foot infections remain one of the major complications leading to a leg loss every 3 seconds due to amputations causing mental trauma and distress. In diabetic foot ulcers aerobes, anaerobes and fungus often interact with each other and form …
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Slaugytojų patirtys tenkinant pacientų, kuriems atlikta apatinių galūnių amputacija, poreikius /
… with diabetes are at higher risk of developing ulcers due to their high susceptibility to infection and complicated wound healing. It is estimated that in developed countries the incidence of diabetic foot ulcers is 2-4 percent per year. About one third of such ulcers do not heal and require …
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Outcome of Ischaemic Foot Ulcers in Patients with Diabetes, with or without Revascularization
… arterial disease (PAD) in regard to outcomes of foot ulcers, factors related to outcomes, and occurrences of new ulcerations and amputations following healing of the initial ulcer. Patients with diabetes and a foot ulcer, consecutively presenting at a multidisciplinary foot centre, with a …
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Molecular imaging of spatio-temporal distribution of angiogenesis in hindlimb ischemia model and diabetic milieu
… can ameliorate the outcome of ischemic disease. Diabetic foot ulcers affect almost 15% of diabetic patients and are the leading cause of amputations worldwide (Yoon et al., 2005). Diminished blood flow because of atherosclerotic occlusive disease of the peripheral arteries of diabetic patients, …