Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 39 for “"Diabetic complications"”.
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Candidate Genes for Late Diabetic Complications
… into account also clinical stages dividing the diabetic patients into noninsulin requiring (NIR), insulin requiring for control (IRC) and insulin requiring for survival (IRS) subgroups. Diabetic complications are the result of chronically elevated blood glucose. Genetic factors are believed to …
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Diabetic Complications in a Native American Population
… 1989). Diabetes Mellitus has multiple complex complications over the long term (Harris, 1996). Complications arise and are more severe without tight glucose control (American Diabetes Association, 1995, p. 4).<br /> The purpose of this random retrospective chart review was to determine rates of …
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GENETIC AND BIOCHEMICAL ANALYSIS OF TYPE 2 DIABETES AND DIABETIC COMPLICATIONS
… produce resulting in high blood glucose. Common complications associated with T2D include cardiovascular disease (CVD), nephropathy or end-stage kidney disease (ESKD), and cognitive decline. CVD is the most common complication with up to 65% of individuals with T2D dying due to CVD. Individuals …
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Cellular Mechanisms Involved in Reactive Carbonyl and Hyperinsulinemia Enhancement of Diabetic Complications
The findings in this thesis demonstrate that (1) hyperinsulinemia negatively impacts B-cell survival (2) and impairs the anti-inflammatory actions of IL-4 in macrophages and finally (3) the reactive carbonyl methylglyoxal enhances chemotherapeutic drug-dependent cytotoxicity. We report that …
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The Long Non-coding RNA Malat1 Regulates Inflammatory Cytokine Production in Chronic Diabetic Complications
… a highly conserved nuclear lncRNA, in chronic diabetic complications affecting the heart and kidneys, specifically with respect to inflammatory cytokine production. Endothelial cells, exposed to various glucose levels, and MALAT1 knockout mice and controls, with or without …
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Hyperinsulinemia and Hyperglycemia Contribute to Diabetic Complications Through Cytokine Resistance and Altered Macrophage Function
Disruption of the cytokine signaling systems responsible for regulating the inflammatory activity of macrophages and direct alterations in macrophage function due to exposure to the conditions of diabetes may play an integral role in the generation of diabetes-associated accelerated …
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HEALTH CONSEQUENCES OF URBANIZATION: EFFECTS OF AIR AND ELECTROMAGNETIC POLLUTION ON THE PREVALENCE OF OBESITY, DIABETIC COMPLICATIONS AND OLFACTORY DYSFUCTION IN DIABETIC PATIENTS.
… pollutants on the prevalence of obesity, T2DM complications and olfactory dysfunction (OD) in two groups of T2DM patients living in different areas of the Lombardy region of Italy with different pollution exposure. Materials and Methods Two comparable groups of T2DM patients coming from an area …
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Loss of function of Gene X protects against α-dicarbonyl stress through the skn-1 pathway in C. elegans
… the damages of α-dcs are reminiscent of diabetic complications. A recent review article identified novel single nucleotide polymorphisms (SNPs) associated with diabetic complications in humans. We performed an unbiased screen for the human SNPs utilizing RNA interference (RNAi) of the …
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Development and application of diabetes care (Type 2) indicators at primary level in the Cape Town metropole region
Since many of the diabetic complications can be prevented by good management, healthcare delivery ought to be of the highest quality possible. Therefore, continuous assessment and improvement of quality of care is important in order to give people with diabetes the care they deserve. This study …
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The Role of Advanced Glycation End Products (AGEs) through the TRPA-1/NRF-2 Activation Pathway in the Neurodegenerative Diseases
… with various age-related diseases including diabetic complications and neurodegenerative diseases. Aging and long-term hyperglycemia causes enhanced production of this highly reactive α-dicarbonyl, which reacts with macromolecules causing irreversible damage of DNA and protein promoting the …
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The effectiveness of methods of videotape instruction with diabetic teaching in the hospital
… of this study was to examine the effects of diabetic teaching using methods of videotape instruction in the hospital. The study focused on measuring the amount of knowledge gained between diabetic patients who viewed a videotape program with and without the presence of a health educator. Data …
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Factors Related to Mental Health Status in Elderly Type 2 Diabetes Patients
… diabetes patients, and their relationship with diabetic parameters. MATERIALS AND METHODS: One hundred and thirty three diabetes patients aged 65 years or over were evaluated for cognitive dysfunction, physical disability, and depressive status, based on questionnaires. Using medical records and …
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Implementing a Diabetic Education Program at Ho'ola Lahui Hawaii Kaua'i Community Health Center
<p>Diabetic complications tend to be common among people with poor diabetes control and can result in debilitating conditions and increased clinical costs. In this aspect, implementing an evidence based diabetic program aims to explore how educational interventions can increase patients …
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Combinational Therapy to Mitigate α-Dicarbonyl Toxicity
… of AGEs has been linked to secondary complications. Secondary complications include diabetic neuropathy, nephropathy and cardiomyopathy. A recently discovered TRPA-1-Nrf-2 pathway is a conserved mechanism in vertebrates and invertebrates that detoxifies α-DCs; however, regulators that …
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Assessing pharmacist's intervention in supporting the management of Type 2 diabetes in a primary care setting.
… of clinical care to prevent the development of diabetic complications. The aim of this study was to compare the impact of a pharmaceutical care diabetic clinic within a primary care setting to standard care on clinical, humanistic and process outcomes in Type 2 diabetes patients. A randomised …
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DEVELOPMENT OF PREDICTIVE MODELS FOR DIABETICS IN ROUTINE LIFE AND EMERGENCY SITUATIONS
… emergency hospital admissions attributed to diabetic complications. In both these cases, development of reliable models to predict the required biochemical outcomes is crucial. These models should have the ability to mimic the physiological conditions, employ practically feasible input and …
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Diabetes, diabetes complications, and their consequences in Mexican-American elders
… describe the epidemiology of diabetes, diabetes complications and their consequences over an 11-year period in Mexican-American elders. Design: This is an 11-year prospective cohort study (1993-1994 to 2004-2005). Setting: This study was conducted among residents of five southwestern states: …
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Effectiveness of Education on Diabetes Control
… biochemical status of patients in the Diabetes Complications Prevention Study (DCPS) at Candler County Hospital in Metter, Georgia. The participants in this study were all active members in the DCPS program. This intervention group was paired to control group members of a similar age and race. A …
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