Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 99 for “"Diabetic Retinopathy"”.
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Inflammatory mediators in diabetic retinopathy
Diabetic retinopathy (DR) is the most feared complication of diabetes with an overall prevalence of 21.9-36.8% and may, if untreated, lead to severe visual disability or blindness. DR is histologically characterized by pericyte and endothelial cell loss, formation of acellular vessel strands, …
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Vessel identification in diabetic retinopathy
Diabetic retinopathy is the single largest cause of sight loss and blindness in 18 to 65 year olds. Screening programs for the estimated one to six per- cent of the diabetic population have been demonstrated to be cost and sight saving, howeverthere are insufficient screening resources. Automatic …
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Premature vascular senescence during diabetic retinopathy
… however, a role for cellular senescence in diabetic retinopathy is unclear. Therefore, the aim of this study is to investigate the senescence profile of human retinal microvascular endothelial cells (HRMECs), to elucidate how this is affected by the diabetic milieu. <br/><br/>HRMECs undergo …
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Role of the sphingomyelin/ceramide pathway in diabetic retinopathy
Thesis (Ph. D.)--Michigan State University. Department of Microbiology and Molecular Genetics, 2010
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The role of VIP family members in diabetic retinopathy
Diabetic retinopathy (DR) is a microvascular complication of diabetes leading to blindness. Hyperglycemic/hypoxic microenvironment concurs to mechanical breakdown of blood-retinal barrier (BRB) as well as the aberrant angiogenesis activating many downstream target genes including inflammatory …
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Detection and Classification of Diabetic Retinopathy Pathologies in Fundus Images
Diabetic Retinopathy (DR) is a disease that affects up to 80% of diabetics around the world. It is the second greatest cause of blindness in the Western world, and one of the leading causes of blindness in the U.S. Many studies have demonstrated that early treatment can reduce the number of …
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Exploring the Role of the Inflammasome Pathway in Diabetic Retinopathy
Background: Diabetic retinopathy (DR) is the leading cause of vision loss among working-age adults worldwide, yet current treatments are inadequate to halt its progression. Studies suggest that dysregulated nucleotide-binding oligomerization domain (NOD)-like receptor protein 3 (NLRP3) inflammasome …
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Vascular breakdown in diabetic retinopathy: Role of connexin43 and possible interventions
Background: Diabetic retinopathy (DR) is a chronic vascular disease of the retina that can lead to vision loss. Current DR therapies, including anti-vascular endothelial growth factors, mainly target late-stage vascular defects and long-term treatments have been shown to contribute to geographic …
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Awareness of diabetic retinopathy among diabetics in the Cape Town Metropole
Objective: To investigate the awareness of diabetic retinopathy (DR) among diabetics in the Cape Town Metropole by assessing: - Whether diabetics know that diabetes can affect their eyes. - Whether the awareness of DR differs according to subtype of diabetes, place of treatment (private versus …
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A Deep Learning Based Pipeline for Image Grading of Diabetic Retinopathy
Diabetic Retinopathy (DR) is one of the principal sources of blindness due to diabetes mellitus. It can be identified by lesions of the retina, namely microaneurysms, hemorrhages, and exudates. DR can be effectively prevented or delayed if discovered early enough and well-managed. Prior studies on …
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Investigation of prolactin-related vasoinhibin in sera from patients with diabetic retinopathy
Wissenschaftlicher Hintergrund: In-vitro-Experimente und in-vivo-Studien mit Nagetieren zeigten, dass die N-terminalen 14,15, 16, 17 und 18 kDa-Fragmente (prolactin-related vasoinhibin, PRL-V) des menschlichen Prolaktins natürliche Inhibitoren der Neovaskularisation in der Retina sind. Diese …
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Optical Coherence Tomography Angiography and wide-field fluorescein angiography in Diabetic Retinopathy
… maculare nei pazienti affetti da edema maculare diabetico e valutare la fattibilità della fluorangiografia con ad ampio campo nella pratica clinica. Materiali e metodi: in questo studio di coorte retrospettivo sono stati inclusi pazienti caucasici con diabete di tipo II e evidenza di edema …
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Benefits and accessibility of OCTA imaging for diabetic retinopathy and macular edema
Diabetic retinopathy (DR) and diabetic macular edema (DME) are among the leading causes of vision loss worldwide. Early detection and timely intervention are crucial in decreasing the risk of vision impairment worldwide. Optical Coherence Tomography Angiography (OCTA) is an emerging imaging …
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Assessment of factors associated with diabetic retinopathy among diabetic patients in Zambia
… the prevalence of diabetes mellitus in Africa. Diabetic retinopathy is a common complication of diabetes mellitus that causes visual impairment and subsequent blindness. Early detection and prompt treatment can prevent blindness in up to 90% of patients. The common risk factors for diabetic …
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Reactive Oxygen Species (ROS) Triggered Delivery System for the Treatment of Diabetic Retinopathy
… to lead to a chronic progressive disease called diabetic retinopathy (DR). It is associated with and characterized by neurodegeneration, increased vascular permeability, progressive vascular occlusion, followed by neovascularization at later stages due to increased expression of vascular …
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Applying Artificial Intelligence and Mobile Technologies to Enable Practical Screening for Diabetic Retinopathy
… concern worldwide. A related complication, Diabetic Retinopathy (DR), affects approximately 1 of 3 people with diabetes and is the leading cause of adult blindness worldwide. Since DR often goes undiagnosed, there has been great interest in using artificial intelligence in the form of Deep …
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Diabetic retinopathy among patients attending university teaching hospitals adult hospital medical clinic in Lusaka
Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus and also a leading cause of visual impairment among people in the working age group. Retinopathy develops overtime in all diabetics and controlling the modifiable risk factors delays its onset and progression. …
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Diabetic retinopathy among patients attending university teaching hospitals adult hospital medical clinic in Lusaka
Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus and also a leading cause of visual impairment among people in the working age group. Retinopathy develops overtime in all diabetics and controlling the modifiable risk factors delays its onset and progression. …
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