Global ETD Search
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Showing 1 to 9 of 9 for “"Diabetic Peripheral Neuropathy"”.
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The Effects of a Novel Therapeutic Intervention in Diabetic Peripheral Neuropathy Patients
… nerves. The most common complication of DM is diabetic peripheral neuropathy. Diabetic peripheral neuropathy causes reduced sensation, reflexes, proprioception, and strength in lower limbs that leads to balance problems. Various manual therapy techniques have not approached a pilot study for …
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The Impact of Type 2 Diabetes and Associated Diabetic Peripheral Neuropathy on Grip Force Control and Hand Function
… with type 2 diabetes (T2D) and associated diabetic peripheral neuropathy (DPN). This might impact their ability to perform essential tasks such as buttoning a shirt, picking up pills, and monitoring blood sugar. Understanding the nature of such deficits is of utmost importance. This …
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Sensory re-weighting for balance control and the effects of ankle foot orthoses and stance width: A comparison of people with diabetic peripheral neuropathy and healthy participants
Background: Diabetic peripheral neuropathy (DPN) is diagnosed clinically as a loss of sensation in the feet and affects over 2 million people in the UK. One of the functional effects of DPN is a decrease in standing stability giving rise to a risk of falls. In an attempt to stabilise in the …
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Insoles to ease plantar pressure in people with diabetes and peripheral neuropathy: a feasibility randomised controlled study with embedded qualitative component
… plantar pressure in people with diabetes and peripheral neuropathy: a feasibility randomised controlled study with embedded qualitative component. Background: Diabetic foot ulceration is a devastating complication of diabetic foot disease. Therapeutic footwear and insoles are one preventative …
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Nerve Fiber Diameter Measurements Using Hematoxylin and Eosin Staining and Brightfield Microscopy to Assess the Novel Method of Characterizing Peripheral Nerve Fiber Distributions by Group Delay
<p>Peripheral neuropathies are a set of common diseases that affect the peripheral nervous system, causing damage to vital connections between various parts of the body and the brain and spinal cord. Different clinical conditions are known to selectively impact various size nerve fibers, which …
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Neuronal Toxicity of Humoral Factors From Patients With Diabetic Neuropathy and Mechanism of Neuronal Death on Cultured Adrenergic Neurons: Studies of Autoimmune Pathogenesis in Diabetic Neuropathy
<p>Diabetic neuropathy is an extremely common medical problem because of the high frequency of diabetes and its complications. Diabetic neuropathy consists of not one, but many patterns of nerve injury, each potentially with its own discrete pathogenic mechanisms. Evidence is accumulating that …
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Novologue Therapy Improves Mitochondrial Bioenergetics and Modulates Transcriptome Changes in Diabetic Sensory Neurons
Diabetic peripheral neuropathy (DPN) is a prevalent diabetic complication with scarce treatment options. Impaired neuronal mitochondrial bioenergetics contributes to the pathophysiologic progression of DPN and may be a focal point for disease management. We have demonstrated that modulating Hsp90 …
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Relationships between subtle ocular changes and microvascular complications in people with type 2 diabetes
… diabetes (T2DM) complications (retinopathy (DR), peripheral neuropathy (DPN), nephropathy (DN)) is limited by insufficient understanding of early pathologies. The eye, prone to diabetic damage, is a microvascular bed accessible for ocular imaging, which has developed rapidly over recent years. …