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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 31 for “"Dextran Sulfate"”.
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Nature of the Interaction of Dextran Sulfate With Phospholipids and Lipoproteins
Made available in DSpace on 2015-05-13T15:26:54Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7616149.PDF: 5336282 bytes, checksum: 60341188a44665fc87045b46ccd7092d (MD5) Previous issue date: 1976
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Elevated colorectal cancer risk in the hnRNP I knockout mice treated with azoxymethane/dextran sulfate sodium
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-10-19 without embargo terms
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TRP channels and a dextran sulfate activated rise in intracellular Ca2+ and Na+ in a subpopulation of double positive thymocytes
… DP) thymocytes when stimulated with dextran sulfate (DxS) and explores several candidate channels that may be involved in this rise. . This [Ca2+]i rise is proposed to mimic a physiological mechanism that influences early DP thymocyte selection and hence the T cell repertoire. During …
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TRP channels and a dextran sulfate activated rise in intracellular Ca2+ and Na+ in a subpopulation of double positive thymocytes
… DP) thymocytes when stimulated with dextran sulfate (DxS) and explores several candidate channels that may be involved in this rise. . This [Ca2+]i rise is proposed to mimic a physiological mechanism that influences early DP thymocyte selection and hence the T cell repertoire. During …
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Inflammation enhanced colon cancer & natural anti-cancer plant compounds
… inflammation-enhanced colon cancer, using the dextran sulfate sodium/ azoxymethane mouse model. GKB (500 µmol/kg diet daily), GE (providing an equal dose of GKB) and broccoli protected against some aspects of inflammation, including cyclooxygenase-2 levels in colonic mucosa. The extract and the …
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Receptor-dependent phagocytosis of <i>Clostridium sordellii</i> by human decidual macrophages
… of CASRs (fucoidan, polyinosinic acid, and dextran sulfate) revealed a role for these receptors in <em>C. sordelli</em>i phagocytosis. Soluble macrophage receptor with collagenous structure (MARCO) receptor prevented <em>C. sordellii</em> internalization, suggesting that MARCO is an …
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Modular Nanoparticles for Selective Cell Targeting
… additional Hep, tetrazine (Tz) modified Hep, or dextran sulfate (DS). The addition of Tz handle on Hep backbone permitted easy modification of NP surface with norbornene (NB) modified motifs/ligands, including inert poly(ethylene glycol) (PEG), cell adhesive peptides (e.g., RGD), and/or …
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Effects of Prebiotics on Gut Bacterial Communities and Healing of Induced Colitis in Mice
… After inducing colitis in a mouse model using Dextran Sulfate Sodium (DSS), prebiotics inulin and oligofructose enriched inulin (OEI) were used as treatments to determine their effects on the gut microbial community, physiological healing process, and immune response in the mice after initial …
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A Larval Zebrafish (Danio Rerio) Model of Adherent-Invasive Escherichia Coli Infections
… AIEC delivery to the gastrointestinal tract, and dextran sulfate sodium (DSS) pharmacologically induced colitis. AIEC colonized the zebrafish gut in higher numbers and persisted for longer compared to non- pathogenic E. coli in the absence of chronic inflammation. Further, bacterial burden and …
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Determining the impact of Heligmosomoides polygyrus infection on the development of colitis
… models of human disease, the oxazolone and dextran sulfate sodium (DSS) models, I found that induction of murine IBD is highly sensitive to diet change and mouse gender. Using the gastrointestinal helminth Heligmosomoides polygyrus (H.polygyrus), I demonstrate that helminth infection …
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Effect of Coconut Oil on Ulcerative Colitis in the Mouse Model
… female C57BL/6 mice by exposing them to 2.5-3% dextran sulfate sodium (DSS) for 5 and 29 days in the acute and chronic models, respectively. Coconut oil treatment was given via food containing 5% coconut oil to three diseased groups in three different regimens: one, preventive group receiving …
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A Study of Pro- and Anti-Nociceptive Factors In A Model of Colitis-Associated Visceral Pain
… pro-nociceptive mechanisms, acute and chronic dextran sulfate sodium (DSS) mouse models of colitis were established and substance P (SP; marker of nociceptor terminals) immunohistochemistry used to investigate changes in immunoreactivity of DRG terminals in the thoracic dorsal horn (segments …
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Non-Psychotropic cannabinoids attenuate visceral pain in colitis
… visceral hypersensitivity use the acute dextran sulfate sodium model. Abdominal pain was quantified by electromyographic recordings of the reflexive contraction of the external oblique muscle in response to colorectal distension using an animal of experimental colitis. Activation of the …
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Colonocyte-Derived Lactate Promotes Enterobacteriaceae Fitness During Non-Infectious Colitis
… the antibiotic streptomycin, a low dose of dextran sulfate sodium (DSS), or both together. In this way, we demonstrated that both inflammation and dysbiosis together were required to induce a maximal production of lactate and for E. coli to utilize lactate. With a genetic mouse model lacking …
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Regulation of Autoimmunity and Inflammation by microRNAs and Environmental Factors
… and the immune system was investigated in the dextran sulfate sodium induced UC mouse model. We demonstrated changes in the colonic intestinal microbiota pattern and immunological alterations of different populations of T cells, dendritic cells and natural killer cells after UC induction.
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Injectable chemokine-releasing gelatin matrices for enhancing endogenous regenerative responses in the injured rat brain
… progenitor cells (aNPCs). We also synthesized dextran sulfate/chitosan polyelectrolyte complex nanoparticles (PCN), which could encapsulate SDF-1[alpha] efficiently and sustain its release for 4 weeks. When used in an in vitro migration assay to fill a core region that was surrounded by an …
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Neuroprotection by Chitosan and Chitosan Nanoparticles
… (chitosan-triphosphate, Chi-TPPNPs and chitosan-dextran sulfate, Chi-DSNPs) were synthesized, with a range of size at 100-300nm and zeta-potentials of 30.65mV and -47.4mV, based on an ionic gelation method. Chi-DSNPs were shown to rescue necrotic BV-2 cells induced by a short incubation of …
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Engineering electroresponsive layer-by-layer thin films
… film components. The release of the polyanion dextran sulfate and the small molecule antibiotic gentamicin sulfate were precisely controlled with an electric potential. When PB is reduced, the negative charge on the particle is doubled, which results in film swelling and a decrease in …
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