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Showing 1 to 2 of 2 for “"Developmental Duplications"”.

  1. Characterization of NHLRC2 gene-edited mice: a model for bovine developmental duplications

    Developmental duplications (DD) is a genetic condition recently characterized in Angus cattle. It is a congenital abnormality where duplication of neural crest derived tissues occurs during embryonic development. A common phenotypic presentation of the condition includes calves born with polymelia …

    uiuc Repository record for Characterization of NHLRC2 gene-edited mice: a model for bovine developmental duplications (opens in a new tab)

  2. CRISPR/CAS9 mediated gene editing for the improvement of beef and dairy cattle

    … causes a heritable abnormality referred to as Developmental Duplications (DD). Calves homozygous for this mutation are affected with a broad range of neural tube defects and commonly exhibit polymelia, which is the presence of additional limbs. The mutation has been identified as a …

    uiuc Repository record for CRISPR/CAS9 mediated gene editing for the improvement of beef and dairy cattle (opens in a new tab)