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Showing 1 to 2 of 2 for “"Detrusor smooth muscle"”.
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The Transient Receptor Potential Melastatin 4 Channel: A New Player in Urinary Bladder Smooth Muscle Function
… bladder (OAB), often characterized by increased detrusor smooth muscle (DSM) contractility, is a highly prevalent disorder affecting ~17% of the US population. The current pharmacotherapy for OAB consists of antimuscarinics which have many adverse side effects and limited efficacy. Therefore, the …
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Ca2+-Activated K+ Channels in Urinary Bladder Smooth Muscle: Functional Role and Potential as Therapeutic Targets for Overactive Bladder
… bladder (OAB), often characterized by increased detrusor smooth muscle (DSM) contractility, is a chronic and highly prevalent condition affecting ~17% of the US population. Alterations in the myogenic or neurogenic activity of DSM serve as a basis for involuntary detrusor contractions associated …