Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Desorption electrospray ionization (DESI)"”.
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Investigation of ion transfer efficiency through multi-channel capillaries for a Desorption Electrospray Ionization (DESI) interface
Desorption Electrospray Ionization (DESI) coupled with mass spectrometry (MS) is an efficient imaging technique for obtaining the spatial distribution of molecular species from a surface. In this study, we experimented with different capillary geometries to maximize the signal intensity of analyte …
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Ambient ionization - mass spectrometry: Advances toward intrasurgical cancer detection
… has focused on the development of ambient ionization – mass spectrometry (MS) for clinical measurements, specifically intrasurgical cancer detection. The molecular differences between normal and cancerous tissue were detected via direct tissue analysis in vitro by touch spray ionization …
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Fourier Transform Based Analysis of Mass Spectra: Disentangling Mass Heterogeneity and Polydispersity
… capture their subtle variances. Advances in soft ionization mass spectrometry (MS) methods such as electrospray ionization (ESI) and desorption electrospray ionization (DESI) have brought together solution phase separation techniques and sensitive gas phase analysis, reducing both sample …
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Development of enabling technologies for single cell analysis with mass spectrometry
… cells efficiently. A variety of microprobe ionization sources are suitable for such analyses, though smaller probe footprints can utilize more densely seeded samples. This dissertation describes two technologies for performing single cell analysis with mass spectrometry. The first, …
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Mass Spectrometry Imaging: Looking Fruits at Molecular Level
… two MSI approaches, namely matrix assisted laser desorption ionization (MALDI) imaging and desorption electrospray ionization (DESI) imaging, have been evaluated and compared by mapping the localization of a range of secondary and primary metabolites in apple and grapes, respectively. The work …
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Mass spectrometry methods for imaging cellular lipids, organelles, and proteins
… charge upon analytes, ion sources have been designed with imaging modalities for visualizing the spatial distributions of ions with specific m/z in samples, including cells and tissues. The ion source utilized determines whether a distinctive label must be incorporated into the biomolecules …
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Application of ambient mass spectrometry in electrochemical systems
Made available in DSpace on 2017-09-29T16:39:22Z (GMT). No. of bitstreams: 3 LIU-DISSERTATION-2017.pdf: 20432445 bytes, checksum: 822e7960639d048f27c3a1682c181f9d (MD5) LICENSE.txt: 4208 bytes, checksum: 26bcd64ff74cb25876083ac4ab0eacd2 (MD5) PROQUEST_LICENSE.txt: 4554 bytes, checksum: …