Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 39 for “"Design of Experiment(DoE)"”.
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Clear, Aqueous Topical Nanomicelle Formulation For Diabetic Macula Edema
The objective of this study was to develop a clear aqueous mixed nanomicellar formulation (NMF) of hydrophobic drugs for diabetic macula edema. The hydrophobic drugs include triamcinolone acetonide (TA), fluocinolonce acetonide (FA) and triamcinolone (T1) were encapsulated with a combination of …
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Integrated optimization system for airbag design and modeling by finite element analysis
"The Finite Element Analysis is widely used in design and modeling of airbags in the automotive industry. Because an airbag is a three-dimensional structure capable of undergoing large deformations with non-linear material properties, usually commercial software is used to conduct the analysis. In …
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Application of the latching control on a wave energy converter
… is proposed to determine the optimum dimensions of a control-free point absorber wave energy converter (WEC). The methodology is based on frequency domain simulation of the WEC oscillations and a statistical analysis method called “design of experiment” (DOE). Then, using the preliminary results, …
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A modified technique in RFID networking planning and optimization
… system is acknowledged as a mature technology often deployed in large scale tracking applications. Implementation issues like cost and effectiveness necessitated research on RFID Network Planning (RNP). The solution typically inspired by nature includes the use of Genetic Algorithm (GA), …
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A Design Study Using Simulation Techniques in Roll Form Production
… where metal strips are fed through a sequence of rolls to achieve a specific cross-sectional profile. This method is vital in the automotive industry for producing high-strength, lightweight components with precision, consistency, and cost-efficiency. This project focuses on optimizing …
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Optimization of parameters of laser non-linear inclined cutting on stainless steel metal
The aim of this research is to develop a laser cutting process model that can predict the relationship between the process input parameters and resultant surface roughness; kerf width characteristics. The research conduct is based on the Design of Experiment (DOE) analysis. Response Surface …
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The Material Separation Process for Recycling End-of-life Li-ion Batteries
End-of-life lithium-ion batteries retired from portable electronics, electric vehicles (EVs), and power grids need to be properly recycled to save rare earth metals and avoid any hazardous threats to the environment. The recycling process of a Lithium-ion Battery Cell/Module includes storage, …
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Evaluation of effect of extrusion process variables on mechanical properties of extruded collagen tubes and effect of post extrusion treatments
This study evaluated the effect of extrusion process variable on mechanical properties of extruded collagen tubes made using a specialized extruder, made by ZOKO Corporation of Czechoslovakia. Three extrusion variables were considered; extrusion speed, linear draw rate and rotation speed. Using …
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Sintering and Characterizations of 3D Printed Bronze Metal Filament
… on their printability, the detailed study of their sintering and characterizations is still missing. In this study, the research is focused on 3D printing of bronze filaments. Bronze is a popular metal for many important uses. The objectives of this research project are to study the optimal …
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Application of Multidisciplinary Design Optimisation Frameworks for Engine Mapping and Calibration
With ever-increasing numbers of engine actuators to calibrate within increasingly stringent emissions legislation, the engine mapping and calibration task of identifying optimal actuator settings is much more difficult. The aim of this research is to evaluate the feasibility and effectiveness of …
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Rapid fabrication of deep-submicron Josephson junctions
A process was designed to fabricate Nb-AlOx-Nb Josephson junctions for quantum computing applications, with the goal of fabricating junctions as small as 0.2 [micro]m in diameter in a time span of roughly two weeks. The process was based on the doubly-planarized all-refractory technology for …
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Data Driven Surrogate Based Optimization in the Problem Solving Environment WBCSim
Large scale, multidisciplinary, engineering designs are always difficult due to the complexity and dimensionality of these problems. Direct coupling between the analysis codes and the optimization routines can be prohibitively time consuming. One way of tackling this problem is by constructing …
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A multi-objective optimisation of a stiffened GFRP sandwich panel with a bilayer core structure, through finite element analysis
… and Von Mises stresses. A preliminary design of the GFRP sandwich panel, based on literature, was analysed through finite element analysis (FEA) on ANSYS Workbench. A parametric model with 432 different configurations was set up. The effects of the input and output variables were …
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Evaluation of hydroxyapatite (HA) from waste eggshell strengthened with ultra high molecular weight polyethylene (UHMWPE) by using injection molding process
This research presents the capability of the waste eggshell as a part of material improvement for the biomedical purpose. Hydroxyapatite ceramics (HA) has been investigated because of its excellent biocompatibility and tissue bioactivity properties. HA from the waste eggshell has been extracted …
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Rational Engineering of Expression Level of Multi-Gene Systems encoding Natural Product Biosynthesis in Streptomyces
It has been shown that genomes of bacteria, especially members of the Streptomyces genus, harbor unprecedented numbers of biosynthetic gene clusters (BGCs) potentially encoding novel compounds. However, cloning and controlled expression of these large BGCs in a heterologous host require tedious …
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Efficient Global Optimization of Multidisciplinary System using Variable Fidelity Analysis and Dynamic Sampling Method
… this dissertation is motivated by reducing the design cost at the early design stage while maintaining high design accuracy throughout all design stages. It presents four key design methods to improve the performance of Efficient Global Optimization for multidisciplinary problems. First, a …
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Development and characterization of electrically conductive thermoplastic based composite materials for fuel cell bipolar plates
… such as lightweight, low cost, ease and speed of manufacturing, and ability to recycle, which make them ideal for a wide range of applications. Composites containing conductive fillers have lower resistivity and better ability to conduct heat and electricity, which make them potential …
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Design and Optimization of Process Parameters in Bio-Gas Production Systems
… that is caused by increasing concentrations of greenhouses gases (CO2 among others). Biogas production is a key technology in the development of sustainable energy supply systems that aims to cover the energy demand using renewable sources and to mitigate greenhouse gas emissions. Biogas …
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Engineering Lipid Nanoparticle-Mediated Delivery of Nucleic Acids to Lymphoid Organs and Immune Cells
… for continued application in the treatment of genetic diseases. Short interfering RNA (siRNA) and microRNA (miRNAs) have been used to silence disease-causing genes. Longer messenger RNA (mRNA) and plasmid DNA (pDNA) have been used to deliver genes whose absence resulted in disease. RNA and …
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Characterization and development of polycaprolactone (PCL)/montmorillonite (MMT)/hydroxapaptite (HA) nano-composites for fused deposition modelling (FDM) process
In this study, characterization and development of polymer nanocomposites filament wire for Fused Deposition Modelling (FDM) was investigated. The polycaprolactone (PCL) filled montmorillonite (MMT) and Hydroxyapaptite (HA) composites were prepared by melting and compounding using a single screw …
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