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Showing 1 to 20 of 79 for “"Desaturase"”.

  1. Genomic Organization of Fatty Acid Desaturase-2 (Fad2 ) and Fatty Acid Desaturase-6 (Fad6) ESTs in Maize

    Mikkilineni, VenugopalUniversity of Illinois at Urbana-Champaign2015

    … indicates that a single enzyme, the delta12 desaturase, converts oleic (18: 1) to linoleic (18:2) by inserting a double bond at the delta-12 position. Fatty acid desaturase-2 (fad2) converts the oleic acid to linoleic acid in the endoplasmic reticulum while the plastidial fatty acid …

    uiuc Repository record

  2. The interaction of xenobiotics and anaesthetic agents with hepatic microsomal stearate desaturase

    Manca, VeronicaDivision of Medical Biochemistry and Structural Biology1980

    … agents, with hepatic microsomal stearate desaturase. The levels of stearate desaturase in the hepatic microsomes were routinely elevated by re-feeding the experimental animals a high carbohydrate diet. The interaction of the xenobiotics with stearate desaturase was assessed by monitoring …

    cape-town Repository record

  3. Chemical Synthesis of Cyclopropenoid Fatty Esters and Their Inhibition Ofthe Liver Desaturase System

    Williams, Joseph LeeUniversity of Illinois at Urbana-Champaign2014

    Made available in DSpace on 2014-12-10T22:38:16Z (GMT). No. of bitstreams: 1 7114994.pdf: 3274102 bytes, checksum: e840d91bee3adcfd069d0996af23c428 (MD5) Previous issue date: 1970

    uiuc Repository record

  4. Isolation and analysis of cotton genomic clones encompassing a fatty acid desaturase (FAD2) gene

    Kongcharoensuntorn, WisatreUniversity of North Texas2001

    … endoplasmic reticulum membranes. Two fatty acid desaturases (designated FAD2 and FAD3) desaturate 75% of the fatty acids in the endoplasmic reticulum. The w -6 fatty acid desaturase (FAD2) may be responsible for cold acclimation response, since polyunsaturated phospholipids are important in …

    unt Repository record

  5. Evidence for the role of delta-6-desaturase in the development of cardiometabolic disease

    Mulligan, Christopher Myles, author, Chicco, Adam J., advisor, Harris, Mary, committee member, Frye, Melinda, committee member, Vanamala, Jairam, committee memberColorado State University. Libraries2014

    … overall aim of elucidating the role of delta-6-desaturase (D6D) in the development of cardiometabolic disease. The experiments tested the general hypothesis that changes in fatty acid membrane composition found to be associated with cardiometabolic disease are attributed to delta-6-desaturase …

    colostate Repository record

  6. The role of sphingosine kinases and dihydroceramide desaturase in regulating senescence in prostate cancer cells

    McNaughton, MelissaUniversity of Strathclyde2018

    … signalling pathway - dihydroceramide desaturase (Des1) - was responsible for promoting a senescent phenotype in LNCaP AI cells. As an adjunct to these findings it is reported here for the first time that the sphingosine kinase 2 inhibitor, ABC294640 …

    strathclyde Repository record

  7. The role of sphingosine kinases and dihydroceramide desaturase in cell survival/apoptosis and inflammation pathways

    Alsanafi, Mariam B.University of Strathclyde2020

    … regarding the role of dihydroceramide desaturase (Degs1) in regulating cell survival/apoptosis and therefore this study primarily examined the molecular basis of the reported opposing roles of Degs1. The sphingosine kinase inhibitor SKi [2-(p-hydroxyanilino)-4-(p-chlorophenyl)thiazole] …

    strathclyde Repository record

  8. Identification of Tissue Distribution and Regulation of Bovine Stearoyl-Coa Desaturase by Hormones and Nutrients

    Campbell, Davina ElaineVirginia Tech2007

    … the tissue distribution of stearoyl-CoA desaturase-1 (SCD) and the regulation of SCD1 protein expression by dietary fat, insulin, polyunsaturated fatty acids (PUFA), and linoleic acid (cis-9, cis-12 18:2). The first study examined tissue distribution of SCD1 protein in Holstein calves …

    vt Repository record

  9. Mice Lacking Delta -6 Desaturase Provide New Insight Into the Essentiality of Highly Unsaturated Fatty Acids

    Stroud, ChadUniversity of Illinois at Urbana-Champaign2015

    This knockout mouse presents itself as an ideal model for the continued investigation of HUFA including AA, DHA and DPA.

    uiuc Repository record

  10. Modification of substrate specificity of thioesterase, reductase, desaturase by MALDI-tof-MS analysis of microbial colonies

    Choe, KisurbUniversity of Illinois at Urbana-Champaign2022

    Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01

    uiuc Repository record

  11. Analyse der Expression von Stearoyl-CoA-Desaturase-1 (SCD1) im zentralen und peripheren Nervensystem der Ratte nach Axotomie

    Ammenwerth, Imke2004

    aachen Repository record

  12. Influence of Loss of Function of the Fatty Acid Desaturase 7 Gene on Photosynthetic Activity and Foliar Redox Status

    Wickramanayake, Janithri Savindya2024

    <p>Fatty Acid Desaturase7 (FAD7) is a chloroplast-localized enzyme that converts 16 and 18 carbon dienoic fatty acids to trienoic fatty acids. The suppressor of prosystemin-mediated response2 (spr2) mutant in tomato (Solanum lycopersicum) and the fad7-1 mutant in Arabidopsis (Arabidopsis thaliana) …

    arkansas Repository record

  13. Stearoyl-COA Desaturase Gene Transcription, mRNA, And Activity In Response To Trans-Vaccenic Acid And Conjugated Linoleic Acid Isomers

    Lin, XiaoboVirginia Tech2000

    … enzymes, and 3) regulation of stearoyl-CoA desaturase (SCD) gene transcription. In the first study, lactating mice were fed 3% linoleic acid (LA), or 2% LA plus 1% stearic acid (SA), 1% TVA, or 1% CLA mixture. Dietary TVA enriched the 9/11CLA content of carcass, liver, and mammary tissue of …

    vt Repository record

  14. Isoflurane : interaction with hepatic microsomal enzymes

    Bradshaw, Jennifer JeanDivision of Medical Biochemistry and Structural Biology1992

    … and human hepatic microsomes and the Δ6- and Δ5-desaturases in rat hepatic microsomes. The interaction of isoflurane with cytochrome P-450 results in its metabolism to fluoride ion and organofluorine metabolites. The cytochrome P-450 isozymes catalysing the defluorination of isoflurane were …

    cape-town Repository record

  15. Impact of fatty acid desaturase (FADS) genotypes on the relationship between serum lipids and dietary fat intake in young Mexican college students

    Vazquez Vidal, ItzelUniversity of Illinois at Urbana-Champaign2014

    Made available in DSpace on 2014-09-16T17:11:50Z (GMT). No. of bitstreams: 2 Itzel_Vazquez Vidal.pdf: 1981856 bytes, checksum: c424238f3b6a362ce0b880e86b24c857 (MD5) license.txt: 4069 bytes, checksum: cf44c5f7be9fd4ce7fb4f5d85a48bc3c (MD5)

    uiuc Repository record

  16. Leptin and the Control of Body Weight and Metabolism: Role for Stearoyl CoA Desaturase-1 and Other Leptin-Regulated Genes in the Liver

    Cohen, Paul

    … leptin-regulated genes were stearoyl-CoA desaturase-1 (SCD-1) and insulin-like growth factor binding protein-2 (IGFBP-2). SCD-1 was specifically repressed during leptin-mediated weight loss, and mice lacking SCD-1 showed markedly reduced adiposity on both a lean (abJ/abJ) and ob/ob …

    rockefeller Repository record

  17. Enhancing the production of Omega-3 polyunsaturated fatty acids in marine diatoms

    Vaezi, RoyahUniversity of East Anglia2015

    … These genes encoded an omega-3-specific Δ6-desaturase, a Δ4-desaturase, a Δ6-elongase and a Δ5- elongase. Overexpression of genes encoding Δ6-desaturase and Δ6-elongase activities in Thalassiosira pseudonana impacted the fatty acid and acyl-CoA profiles of this model centric diatom. Changes …

    east-anglia Repository record

  18. Ein neuer Syntheseweg für wertvolle Fettsäuren in Saccharomyces cerevisiae und Arabidopsis thaliana

    Hoffmann, Mareike2012

    … testen. Neue Gene für CoA-spezifische Δ6- und Δ5-Desaturasen wurden aus den Mikroalgen Mantoniella squamata und Ostreococcus tauri isoliert und die rekombinanten Enzyme durch heterologe Expression in Hefe charakterisiert. Eine neue Δ6-Desaturase aus M. squamata zeigte ausgeprägte Spezifität für …

    goettingen Repository record

  19. Validation and Application of a Novel Target-Based Whole-Cell Screen to Identify Antifungal Compounds

    DeJarnette, Christian Alexander2021

    … <p>Both the fungal fatty acid synthase and desaturase have been established as essential for fungal growth, virulence in a systemic infection, and are structurally distinct from their mammalian counterparts. However, there has been little success in developing clinically relevant inhibitors …

    tenn-hsc Repository record

  20. The effects of feed supplemented with omega-3 polyunsaturated fatty acids on cultured abalone

    Mateos, HintsaVictoria University2012

    … on tissue fatty acid composition, expression of desaturase and elongase genes and growth performance of adult cultured Jade Tiger hybrid abalone. It also examined the effects of replacement of FO with vegetable oils on fatty acid composition, expression of desaturase and elongase genes, and …

    vu-aus Repository record

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