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Showing 1 to 4 of 4 for “"Department of Biochemical Engineering"”.

  1. Characterisation of the structural stability of transketolase under biocatalytically relevant conditions

    … regulation. TK catalyses the interconversion of sugars by transferring a two-carbon ketol unit from a ketose donor substrate to an aldolase acceptor substrate. It is also an important biocatalyst in stereo-specific carbon-carbon bond synthesis with potential industrial application for the …

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  2. Characterisation of chromatography adsorbents for antibody bioprocessing

    Currently the purification of monoclonal antibodies for therapeutic purposes is reliant on protein A affinity chromatography. The rapid growth of this class of therapeutic and their high value makes the understanding of protein A chromatography an important target. There is a range of commercially …

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  3. Centrifugal recovery of embryonic stem cells for regenerative medicine bioprocessing

    In order to realise the potential of embryonic stem (ES) cells as a regenerative medicine, it is crucial that economical, robust and scalable bioprocesses be established. Because bioprocesses irrevocably define the safety and efficacy of any biologically derived product, an understanding of the the …

    ucl Repository record for Centrifugal recovery of embryonic stem cells for regenerative medicine bioprocessing (opens in a new tab)

  4. Tube-forming device design for the creation of cell-integrated alginate tubes

    This thesis describes a generic system capable of forming cell-populated alginate tubes either by seeding cells within its lumen, or integrating cells within the tube walls. The applications of an alginate tube are as diverse as applications of alginate beads, and could be used with many types of

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