Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Dental Pulp Stem Cells"”.
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Cytoskeletal Gene Expression in Dental Pulp Stem Cells Under Inflammation-Induced Hypoxia
Introduction: Dental pulp stem cells (DPSCs) play a crucial role in repair and regeneration of dentin-pulp complex through differentiation into odontoblasts. Upregulation of key cytoskeletal genes have been shown to impact differentiation of DPSCs into an odontogenic lineage. Additionally, chronic …
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Human dental pulp stem cells as a patient-in-a-dish model for Charcot-Marie-Tooth disease type 1A
… model voor waarbij gebruik wordt gemaakt van dentale pulpa stamcellen (DPSC's) afkomstig van gezonde en CMT1A donoren, samen met gezonde iPSC afgeleide motorneuronen (iPSC-MN's), om een volledig humaan CMT1A patiënt-in-een-petrischaal te creëren dat de kenmerken van CMT1A in vitro nabootst. …
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Development and evaluation of the innovative 3D printed scaffolds for bone regeneration in vitro and in vivo /
… and osteoinductive (enhanced with dental pulp stem cells or their extracellular matrix) scaffolds in the Wistar rat critical-size calvarial defect model were analysed in the study. Moreover, the obtained results were compared with one of the most well-known and widely used …
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A Novel Biomimetic Scaffold for Guided Tissue Regeneration of the Pulp - Dentin Complex
… trauma to the front teeth which results in pulp damage. If left untreated, these teeth are susceptible to premature fracture/loss under daily stresses. In cases of adolescent tooth loss, teenagers cannot get dental implants until after the growth spurts; their only option is using removable …
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Identifying Diagnostic Biomarkers: Gene Expression Profiling Leptin in Dental Pulp Tissue
… in normal and inflammatory conditions of dental pulp tissues. LEP/LEPR activity is linked to potential immunomodulation responses during bacterial-induced inflammatory conditions. Additionally, there is substantial association of LEP in dental pulp stem cells (DPSCs), odontoblast …
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Neuroinflammatory consequences of rhinovirus infection in the human airway
… model was derived from differentiation of human dental pulp stem cells towards a neuronal phenotype, termed peripheral neuronal equivalents (PNEs). PNEs were infected for 2, 6, 24, 48 and 72 hrs with major group RV-A16, or minor group RV-A1b, at a range of multiplicities of infection (MOI) (0.01 …
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ATP, TRP channels and airway neuronal sensitisation
… by working with primary bronchial epithelial cells (PBECS) and an in-Vitro human sensory neuronal model differentiated from human dental pulp stem cells termed peripheral neuronal equivalents (PNEs). TRP channels are thought to play a role in the neuronal hyperresponsiveness responsible for …
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Synthesis and Characterization of Methacrylated Hyaluronan-Based Hydrogels for Tissue Engineering
… use of tissue engineering applications involving stem cells, human dental pulp stem cells (DPSCs) were exposed to both HA-AEMA macromer and hydrogels for cytotoxicity and encapsulation studies by MTT using mitochondrial based assays and fluorescent viable cell staining respectively. Results of our …
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Molecular and Cellular Investigations of Prader-Willi Syndrome
… imprinting center defects (1-3%). Here, we used dental pulp stem cells (DPSC), differentiated to neuronal cultures, to investigate the molecular and cellular phenotypes of PWS neurons. DPSC are multipotent stem cells that accurately recapitulate the epigenetic signature of embryonic stem cells …
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MRGX1-TRPAI in inflammatory pain signalling
… models of human nociceptors from 1) neural crest stem cells using a previously validated method and 2) human neural progenitors using magnetic-activating cell sorting (MACs) technology, both derived from human dental pulp as well as an ex-vivo model of trigeminal nerves. Immunofluorescent staining …
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Neural Crest Contributions to Dental Pulp Stem/Progenitor Cells and Craniofacial Structures: Alveolar Processes, Tongue and Temporomandibular Joint
… in vertebrates, is crucial to craniofacial and dental development. Populations of multipotent stem cells have been identified in various dental tissues including dental pulp. Hence, identification of multipotent cells of neural crest lineage within dental pulp and delineation of neural crest …