Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Dense Granule Secretion"”.
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Molecular Mechanisms Underlying Differential Regulation of Platelet Dense Granule Secretion by Protein Kinase C delta
… the murine platelets lacking PKCδ, PAR4-mediated dense granule secretion was inhibited, whereas GPVI-mediated dense granule secretion was potentiated. These effects were statistically significant in the absence and presence of thromboxane A2 (TXA2). Furthermore, TXA2 generation was differentially …
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Adiponectin : a novel circulating anti-thrombotic factor in humans?
… the role of platelet secondary mediators, granule secretion and intracellular signalling events using a series of receptor antagonists and inhibitors.The experimental data demonstrated that gAd-stimulated aggregation required adenosine diphosphate (ADP) and thromboxane A2 (TxA2) to achieve …
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NOVEL REGULATORS OF GPVI-MEDIATED PLATELET ACTIVATION
… leads to platelet shape change, granular secretion, thromboxane A2 (TXA2) synthesis, and integrin IIb3-mediated platelet aggregation and thrombus formation. In the past, a lot of effort has been placed in understanding GPVI and its signaling in platelets, however, much is still unknown. …
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The Regulation of Phosphorylation Events in Platelets
… and causes the platelets to secrete their granule contents. This generated thromboxane as well as constituents released from dense granules such as ADP, and serotonin, play an essential role in potentiating the platelet response through activation of other surface receptor mediated …