Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Dengue viruses"”.
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Biochemical, molecular and microscopic studies on mosquitoes with special emphasis on Wolbachia infections, diagnostic assessment of Dengue viruses and biological control of Dengue vectors
… of debilitating diseases such as malaria, dengue, yello and west nile fever as well as lymphatic filariasis. The knowledge on the biology of mosquitoes, pathogens and parasites transmitted by them is essential for a better control of both insects and diseases they are transmitting. This …
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DENVax live attenuated chimeric dengue vaccine
Dengue viruses are endemic in regions inhabited by roughly one half of the world’s population and can cause symptoms ranging from a headache and fever to even death. There is no vaccine to prevent infection by dengue viruses and the only current protection and prevention is mosquito control. The …
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Sylvatic dengue: evolution, emergence, and impact on human health
Dengue viruses (DENV) are the most important arboviral pathogens in tropical and subtropical regions throughout the world. Transmission includes a sylvatic, enzootic cycle between nonhuman primates and arboreal mosquitoes of the genus Aedes, and an urban, endemic/epidemic cycle between Aedes …
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A Structural Perspective of Antibody Neutralization of Dengue Virus
<p>The four dengue viruses: DENV) are mosquito-borne flaviviruses and are considered the world's most significant arboviruses in terms of worldwide disease burden. Symptoms of dengue disease are classified into dengue fever, a mild, febrile illness, and the potentially fatal severe dengue, which …
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Genetic modification of the homomorphic sex chromosomes in the yellow fever mosquito Aedes aegypti provides novel insights and tools for biocontrol
… spread of Zika, yellow fever, chikungunya, and dengue viruses. Current methods of preventing the spread of arboviral diseases rely primarily on population control of the mosquito vector. These practices are insufficient as millions of arboviral infections still occur each year. Genetic …
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DEVELOPMENT OF E-SRS (ENVIRONMENT-SENSING RESPONSE SYSTEM) AS A NOVEL METHOD TO DISTINGUISH GENETIC ENVIRONMENTS AND RESOLVE CLOSELY RELATED NUCLEIC ACID SEQUENCES
… as Mfs, Mfr1, and Mfr2; 2) 4 common serotypes of Dengue viruses, denoted as D1, D2, D3, and D4. We developed a computational algorithm in Perl that greatly automated the design and assessment of e-SRS Mz-based sensors. Our seven e-SRS sensors were optimised to specifically detect their sNTS (19 to …
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Development, Characterization, and Use of Molecular Tools to Study Immune-Driven Zika Virus Evolution
Emerging viruses represent a significant threat to human health. Understanding the drivers of emergence, such as viral evolution, is a critical avenue to combat these pathogens. One specific group of emerging pathogens of interest is flaviviruses. Flaviviruses are arthropod-borne viruses …
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Isolation and characterization of dengue virus membrane-associated replication complexes from Aedes aegypti
… has proposed that a balance exists between dengue virus (DENV) replication in Aedes aegypti and the mosquito's RNA interference (RNAi) based antiviral response. Here, we have isolated and characterized membrane-bound replication compartments from mosquito cell culture and Ae. aegypti to …