Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 192 for “"Dengue"”.
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Expressão das proteínas não-estrutural 1 (NS1) dos vírus Dengue-1, Dengue-3 e Dengue-4 em Pichia pastoris
A dengue é uma doença amplamente distribuída pelo mundo, e representa um grande problema de saúde pública em vários países. As manifestações clínicas podem variar desde uma síndrome viral inespecífica e benigna, até um quadro grave e fatal de doença hemorrágica com choque. O diagnóstico na sua fase …
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Dengue Virus Host Factors
<p>Dengue fever and dengue hemorrhagic fever are estimated to afflict 50-100 million people annually and are caused by one of the four serotypes of dengue virus. Dengue virus is carried and transmitted to humans by mosquitoes of the Aedes genus. Given the broad geographic distribution of Aedes …
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DENVax live attenuated chimeric dengue vaccine
Dengue viruses are endemic in regions inhabited by roughly one half of the world’s population and can cause symptoms ranging from a headache and fever to even death. There is no vaccine to prevent infection by dengue viruses and the only current protection and prevention is mosquito control. The …
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Immunoepidemiological Modeling of Dengue Viral Infection
Dengue viral infection is a mosquito-borne disease with four distinct strains, where the interactions between these strains have implications on the severity of the disease outcomes. The two competing hypotheses for the increased severity during secondary infections are antibody dependent …
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Mathematical Modeling of Dengue Viral Infection
In recent years, dengue viral infection has become one of the most widely-spread mosquito-borne diseases in the world, with an estimated 50-100 million cases annually, resulting in 500,000 hospitalizations. Due to the nature of the immune response to each of the four serotypes of dengue virus, …
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Factores asociados con la presencia de dengue grave en pacientes colombianos con diagnóstico confirmado de dengue 2013-2015
Introducción: El dengue es el arbovirus más importante del mundo. Colombia es hiperendémico por esta enfermedad y su complicación severa está presente en la población colombiana. Objetivo: Determinar los factores sociodemográficos, clínicos y de laboratorio que se asocian con la presencia de dengue …
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A non mouse-adapted dengue virus strain as a new model of severe dengue infection in AG129 mice
The spread of dengue (DEN) worldwide combined with an increased severity of the DEN-associated clinical outcomes have made this mosquito-borne virus of great global public health importance. Progress in understanding DEN pathogenesis and in developing effective treatments has been hampered by the …
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Dengue and development: a critical political ecology
<p>Policies for the control of dengue fever often construct the mosquito-borne virus as a disease of poverty, and call for disease control through “development” to meet the needs of poor populations and impoverished or unsanitary spaces. However, exceptions to the narrative of a rich/poor dengue …
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Dengue Fever: An Examination and Case Study
Dengue Fever is a mosquito-borne disease found primarily in tropical regions of the Earth. Although not prevalent in much of the western world, dengue appears to be an emerging virus, which prompts a need for further understanding. The purpose of this study is to provide a general overview of the …
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Weather, climate change and dengue in Mexico
… have estimated empirical relationships between dengue, weather, and El Ni˜no in several regions of the world. Some of these studies used their model estimations to predict the potential impacts of climate change on the future distribution of dengue. Often, these studies have sidestepped elements …
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Dengue virus and West Nile virus protease inhibitors
Dengue virus and West Nile virus are important mosquito-borne pathogens of Flaviviridae family affecting millions of people worldwide and causing a severe global healthcare threat. However, currently there are no approved effective antiviral drugs or vaccines available for the treatment of virus …
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Dengue virus infection. Clinical assessment, pathophysiology and management.
Contains fulltext : 49261.pdf (Publisher’s version ) (Open Access)
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A survey of mathematical models of Dengue fever
… paper, we compare and contrast five models of Dengue fever. We evaluate each model using different scenarios and identify the strenghts and wecknesses of each of the model</p>
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Short-to-medium term dengue forecast in Singapore
Dengue fever is currently the fastest spreading mosquito-borne disease in the world, and a substantial public health problem due to its geographic spread, intensity, and resulting economic impact. The disease is endemic in Singapore, and has caused multiple outbreaks of unprecedented magnitude in …
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Evaluation of a Tetravalent DNA Vaccine against Dengue: Integrating Biochemical Studies on Dengue Virus Envelope Protein to a Domain-Based Antigen Design.
Dengue virus (DENV) is among the most important mosquito-borne human pathogens worldwide. Concerns regarding the effectiveness of Dengue vaccines together with emergence of Zika virus (ZIKV) have reignited the interest for new vaccines using alternative approaches. Given that the envelope …
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A Structural Perspective of Antibody Neutralization of Dengue Virus
<p>The four dengue viruses: DENV) are mosquito-borne flaviviruses and are considered the world's most significant arboviruses in terms of worldwide disease burden. Symptoms of dengue disease are classified into dengue fever, a mild, febrile illness, and the potentially fatal severe dengue, which …
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Sylvatic dengue: evolution, emergence, and impact on human health
Dengue viruses (DENV) are the most important arboviral pathogens in tropical and subtropical regions throughout the world. Transmission includes a sylvatic, enzootic cycle between nonhuman primates and arboreal mosquitoes of the genus Aedes, and an urban, endemic/epidemic cycle between Aedes …
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