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Showing 1 to 3 of 3 for “"Denaturing High-Performance Liquid Chromatography (DHPLC)"”.

  1. Sequence Detection and Comparative Analysis of the Hv1 and Hv2 Control Regions of Human Mitochondrial DNA by Denaturing High-Performance Liquid Chromatography

    … was the evaluation and forensic validation of Denaturing High-Performance Liquid Chromatography (DHPLC) as a sequencingindependent means of detecting the presence of sequence differences in pair-wise mixtures of non-concordant amplicons of human mitochondrial DNA (mtDNA). The reproducibility …

    denver Repository record for Sequence Detection and Comparative Analysis of the Hv1 and Hv2 Control Regions of Human Mitochondrial DNA by Denaturing High-Performance Liquid Chromatography (opens in a new tab)

  2. Functional study of ubiquitin C-terminal hydrolase-L1 gene promoter haplotypes

    … (Ser18Tyr), were identified using both denaturing High Performance Liquid Chromatography (dHPLC) and DNA sequencing analysis. In relation to the translational start site, the novel SNPs elucidated were: A-307G, A-306G, G-234A, A-24G, C-16T, G12A and G21A. Restriction Fragment Length …

    soton Repository record for Functional study of ubiquitin C-terminal hydrolase-L1 gene promoter haplotypes (opens in a new tab)

  3. Common ABCA4 mutations in South Africans: frequencies, pathogenicity and genotype-phenotype correlations

    … SNaPshot PCR, allele-specific PCR (AS-PCR) and denaturing high performance liquid chromatography (dHPLC) analysis were used to screen for the seven mutations in a patient cohort and a control cohort. A high detection rate of bi-allelic disease-causing mutations in total of 28/72 patients (i.e. …

    cape-town Repository record for Common ABCA4 mutations in South Africans: frequencies, pathogenicity and genotype-phenotype correlations (opens in a new tab)