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Showing 1 to 6 of 6 for “"Demineralized bone matrix"”.
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Bone growth following demineralized bone matrix implantation requires angiogenesis
… endochondral ossification in mice by implanting demineralized bone matrix (DBM) proximal to the femur to induce ectopic bone formation. TNP-470, a drug known to be anti-angiogenic, was used to inhibit vascularization during the time course of de novo bone formation in order to define the role of …
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Synthetic Hydrogel Delivery of Growth Factors and Demineralized Bone Matrix for Bone Augmentation
… hydrogel delivery of growth factors and demineralized bone matrix (DBM) for bone augmentation. Our motivation rests on observed weaknesses of current clinical approaches to bone augmentation, which synthetic hydrogels hope to overcome based on non-invasive application, contouring, …
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Investigation of adipose-derived mesenchymal stem cells interaction with electrospun demineralized bone matrix nanofiber scaffolds
Nanofiber demineralized bone matrix (DBM) scaffolds were fabricated by electrospinning, and their ability to support cell adhesion and cell viability of murine adipose-derived mesenchymal stem cells (AD-MSCs) for short-term in culture media was investigated. Poly (ε-caprolactone) (PCL) scaffolds …
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The synergistic effect of pulsed electromagnetic fields and demineralized bone matrix on the osteogenic differentiation of mesenchymal stem cells
Orthopaedic bone grafting continues to be a mainstay in the treatment of non unions and other difficult to heal bone defects. Tissue engineering strategies have focused on providing bone graft materials that are osteoconductive, osteoinductive and osteogenic in order to achieve optimal bone …
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The Quantitative Assessment of Osteoinductivity of Human Demineralized Bone Matrix and cDNA Array Analysis of Osteogenic Differentiation in Human Periosteal Cells
<p>Demineralized bone matrix (DBM) has been extensively utilized in orthopeadic, periodontal, and maxillofacial applications. DBM comprises bone morphogenetic proteins (BMPs) that are essential regulators for endochondral bone formation. The current study was undertaken to establish the …
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The Assessment of Osteoinductivity of Human Allograft Demineralized Bone Matrix by <i>In Vivo</i> and <i>In Vitro</i> Assay Models
… (osteoinductivity) is a very important aspect of demineralized bone matrix (DBM) as a biomaterial. This study is directed at establishing qualitative and quantitative assays of the osteoinductivity of human DBM. Further aspects of this study include an assessment of the effects of the production …