Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Delta-like 1"”.
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Engineered microenvironments for studying liver progenitor differentiation
… we demonstrated that exogenous Jagged-1, Delta-like 1, and Delta-like 4 within the cellular microarray format was sufficient to induce cholangiocytic differentiation. Further, by combining Notch ligand microarrays with shRNA-based knockdown of Notch ligands, we systematically examined the …
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The Role of Cdx in Intestinal Development
… Cdx operates upstream of Notch ligand Delta-like 1 (Dll1) in endoderm and mesoderm derivatives, demonstrating that Cdx function is similar in different lineages. Finally, Cdx2 cannot fulfill the requirement for Cdx1 in regulation of its own promoter in the intestine. This is the first …
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Novel Notch signalling dynamics within the molecular oscillator underlying vertebrate segmentation
… Notch signalling ligand and receptor in the PSM, Delta-like 1 (Dll1) and Notch1, are shown to vary dynamically across the PSM of both chick and mouse. This proposes that the signalling components mediating intercellular coupling of pulsatile gene expression themselves exhibit oscillatory …