Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"Delivery carriers"”.
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Stable Polymer Micelle Systems as Anti-cancer Drug Delivery Carriers
… that might be used as ultrasonic-activated drug delivery carriers were synthesized and investigated. These polymeric micelle systems were Plurogel®, Tetronic®, poly(ethylene oxide)-b-poly(N-isopropylacrylamide) and poly(ethylene oxide)-b-poly(N-isopropylacrylamide-co-2-hydroxyethyl …
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Novel Biomimetic Polymeric Nanoconjugates as Drug Delivery Carriers for Poorly Soluble Drugs
… nanoconjugate present a novel tool for the delivery of ibuprofen with potential application for transdermal delivery.
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Calcium Phosphate Nanoparticle Synthesis and Manufacture using Microwave Processing for Biomedical Applications
… scaffolds for bone regeneration and as gene delivery carriers. However, significant problems related to their synthesis have limited their clinical use.</p><p>Conventional processing produces CaP with low crystallinity and large particulates which contributes to the overall brittleness of …
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Design of Functional Polymeric Micelles as a Carrier for Anticancer Drug Delivery
… nanoparticles are frequently utilized as drug delivery carriers due to their particular core/shell structure, ease of functionalization, sustained circulation in the blood and its ability to passively accumulate in leaky tumor tissues. Two important factors that should be considered in the …
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Magnetically-driven Therapeutic Agents Delivery System using Iron Oxide Nanocages and Enhancement of Exosome Secretion, a Potential Biological Drug Delivery Carrier
… on using 20 nm iron oxide nanoparticles as siRNA delivery carriers under the alternating magnetic field and the development of a method to amplify the secretion of 150 nm exosomes from the cells, which could potentially use as a biological drug carrier.</p> <p>Chapter 2 discusses a magnetically …
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Multimodal Imaging of Protein-Based Biomaterials for Delivering Chemo-Agent Cargo for Glioblastoma Treatment in a Murine Model
… (TRAP), present meaningful potential as drug delivery carriers. These materials enable the controlled, slow release of poorly soluble chemotherapeutic agents, such as doxorubicin (Dox), while potentially reducing systemic off-target effects. In collaboration with multiple NYU labs, this study …
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Qhatuyki Store modelo de negocio para pequeños distritos urbanos
… bazaar stores, grocery stores, etc.) with delivery carriers; to be able to offer their consumers the experience of online shopping and delivery express service, without the need to have a credit card or a bank account to make their payments. Buyer users will be able to purchase the products …
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Layer-by-Layer Nanoparticles for Targeted Delivery and Treatment of Ovarian Cancer
… tissue and poor pharmacokinetics. Targeted drug delivery carriers can reduce systemic toxicity caused by off-target interactions, increase drug solubility and stability in physiological fluids, and improve efficacy through enhanced targeting and intracellular delivery to cancer cells. …
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Nanoparticle-coated polymeric microbubbles for revascularization
… applications, nanoparticles work as drug delivery carriers in recent decades due to their features on size and transport properties compared to drug molecules alone. Modification of nanoparticle surface, structure, and its fabrication methods has been done by researchers to improve the …
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Advanced analytical strategies to determine biomedical parameters for medical diagnostics, drug delivery, and therapy
… that have the potential to be used as drug delivery carriers. Firstly, a dual-core fiber-optic pH micro-probe was developed which can be used within the biologically relevant pH range from 6.20 - 7.92 (R<sup>2</sup> = 0.9834). Secondly, a targeted HPLC-MS/MS protocol was developed to …
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Water-Soluble Deep-Cavity Cavitands: Synthesis, Molecular Recognition, and Interactions with Phospholipid Membranes
… phenomena and have potential use in drug delivery. The host octaacid (OA) has been particularly well-characterized, but studies are limited to basic pH because of limited host solubility.</p> <p>Herein we report an improved synthesis of OA and the syntheses of three new water-soluble …
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Surface Engineering of Protein Nanoparticles for Intranasal Delivery
Intranasal delivery of vaccines offers a promising alternative approach to invasive intramuscular injection, with additional benefits such as inducing mucosal antibodies and cellular responses to neutralize pathogens before entering systemic circulation. However, nasal secretions and mucosa are …
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Dairy ingredients-based emulsions and beta-carotene delivery
… and thus their health benefits. Therefore, the delivery of these compounds requires protective mechanisms. Emulsion-based delivery systems are becoming some of the most ideal microencapsulation carriers for these lipophilic bioactive components, and tailored structures of emulsions potentially …
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Novel antimicrobial combinations for treatment against pathogens associated with infected diabetic foot ulcers
… their encapsulation into efficient drug delivery carriers is crucial to increasing their bioavailability and retention time. Lipodisq® (LQ) nanoparticles consist of a circular phospholipid bilayer that is stabilized by an annulus of polystyrene-co-maleic anhydride (PSMA). PSMA is used …
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Preparation and analysis of novel tumour-targeted delivery systems for prostate cancer therapy
… treatment of prostate cancer. Non-viral gene delivery is emerging as potential safer alternative to the use of viral vectors for the treatment of various gene related diseases including cancer. Although non-viral vectors may not be as effective as the viral ones, the continuous research on …
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Ionic Copolymer-Magnetite Complexes for Magnetic Resonance Imaging and Drug Delivery
… of magnetite-ionic copolymer complexes as nanocarriers for drug delivery and magnetic resonance imaging. The polymers included phosphonate and carboxylate-containing graft and block copolymers. Oleic-acid coated magnetite nanoparticles (8-nm and 16-nm diameters) were investigated. Cisplatin and …
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Design, Synthesis and Characterization of Porous Silica Nanoparticles and Application in Intracellular Drug Delivery
Nanoparticle mediated drug delivery approaches provide potential opportunities for targeting and killing of intracellular bacteria. Among them, the porous silica nanoparticles deserve special attention due to their multifunctional properties such as high drug loading, controlled drug release and …
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Nanocarriers for nose-to-brain delivery: a novel strategy for the treatment of CNS disorders
… The blood-brain-barrier (BBB) precludes the delivery of drugs to the brain, preventing the therapy of a number of neurological disorders. In the last 20 years, intranasal (IN) administration has gained great attention in research and has been investigated with regard to its feasibility to …
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Microfluidic assembly of zein microcapsules
… masking, nutrient protection, and probiotics delivery. The controlled release property of core materials from the microcapsules is one of the key factors to achieve the essential goal of incorporating microcapsules in foods. Despite the extensive research on microencapsulation in the past, it …
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Mixed Polysaccharide Esters for Amorphous Solid Dispersion Oral Drug Delivery Vehicles
… mixed ester derivatives for oral drug delivery applications. Cellulose and cellulose esters have been extensively studied and utilized for different applications such as separation membranes, sustainable plastics, and enteric coatings in oral drug delivery carriers. We sought to exploit …
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