Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Delayed cell cycle progression"”.
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The Effect of Mitochondrial Dynamics on Cell Cycle Progression
… segregation is the most critical event during cell cycle progression and appears to be precisely controlled by several defined machineries. On the other hand, the mechanisms by which cellular organelles duplicate and partition into two daughter cells during cell division have been barely …
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Development of a novel approach to expand umbilical cord blood-derived haematopoietic stem/progenitor cells ex vivo for clinical transplantation
… source of haematopoietic stem/progenitor cells (HSPC) for haematopoietic stem cell transplantation (HSCT). One factor limiting the wider use of UCB for transplantation is the relatively low cell dose from a UCB unit compared to bone marrow (BM) and peripheral blood (PB). To overcome this …
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THE ROLE OF THE RNA-BINDING PROTEIN TRISTETRAPROLIN IN CERVICAL AND COLORECTAL CANCERS
… anti-proliferative capacity in cervical cancer cells through p53 stabilization and telomerase inhibition leading to cellular senescence. This growth-suppressive phenotype is the functional consequence of TTP's ability to promote rapid ARE-mRNA decay of the cellular ubiquitin ligase E6-AP, which …
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Targeting DNA Repair in Prostate Cancer: Therapeutic Combinations & Disease Models
Targeting prostate cancer cells with DNA repair inhibitors presents an opportunity to improve outcomes in patients with poor prognosis cancers. There are multiple reasons which rationalise targeting DNA repair in prostate cancer, including the enrichment of DNA repair genetic alterations in men …