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Showing 1 to 2 of 2 for “"Definitive Haematopoiesis"”.
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Modelling Embryonic Haematopoiesis Using In Vitro State-of-art Gastruloid Culture
… to produce HSPCs from mouse ES cells and model haematopoiesis which occurs at the aorta-gonad-mesonephros (AGM) region of the mouse embryo. In this project, the gastruloid culture protocol is modified to maintain a gastruloid (gastrulation organoid) for up to 216 hr by introducing a 2iLIF …
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The role of GATA-1 isoforms in haematopoiesis
… and physiological role of GATA-1s in haematopoiesis. Some insight has been gained into the pathological role of GATA-1s by creation of a GATA-1s knock-in transgenic mouse and by experiments looking at the ability of GATA-1s to rescue GATA-1 deficient embryonic stem (ES) cell lines. …