Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 68 for “"Deep Brain Stimulation"”.
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Deep Brain Stimulation for Tourette Syndrome
… (TS). The International Tourette Syndrome Deep Brain Stimulation (DBS) Public Database and Registry is a multinational collaborative effort designed to share data and improve the quality of outcomes research in the treatment of TS with DBS. , recently described by Martinez-Ramirez et al in …
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Understanding Autonomic Control via Human Deep Brain Stimulation
… of higher cortical areas, basal ganglia, and brainstem areas that are important in the control of the autonomic nervous system (ANS). This thesis concentrates on the control of the respiratory and cardiovascular systems both alone and in combination in the context of exercise. Deep Brain …
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Digitally-Controlled Deep Brain Stimulation Lead Implant System
<p>Deep brain stimulation, the treatment of disorders by applying electrical stimulation to brain tissue, is a relatively new field of medicine with great potential to provide cures for neurological disorders. It utilizes a system very similar to a cardiac pacemaker and lead to electrically …
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Analysis and Design of Electrodes for Deep Brain Stimulation
<p>Deep brain stimulation (DBS) electrodes are intended to stimulate specific areas of the brain to treat movement disorders including essential tremor, Parkinson's disease and dystonia. An important goal in the design of next generation DBS electrodes is to minimize the power needed to stimulate …
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Behavioral Pharmacological Analysis of Deep Brain Stimulation Following Nerve Injury
Treatment of neuropathic pain remains a major unmet public health problem. Serious concerns arise over misuse of prescription opioids in chronic pain patients, a drug class representing the fastest growing substance abuse problem in the United States. Ascending pain pathways overlap significantly …
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Towards Closed-Loop Deep Brain Stimulation: Behavior Recognition from Human STN
<p>Deep brain stimulation (DBS) provides significant therapeutic benefit for movement disorders such as Parkinson’s disease (PD). Current DBS devices lack real-time feedback (thus are open loop) and stimulation parameters are adjusted during scheduled visits with a clinician. A closed-loop DBS …
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Balance performance in people with Parkinson’s disease. Effects of subthalamic Deep Brain Stimulation.
… overall aims of this work were to investigate if Deep Brain Stimulation in the subthalamic nuclei (STN) affected balance, fear of falling and falls in people with Parkinson's disease. The effect of STN stimulation alone was investigated in Papers I, II and III. The participants were evaluated …
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Quantifying the pathways modulated by deep brain stimulation for essential tremor using computational modeling
Deep brain stimulation (DBS) within or near the ventral intermediate nucleus of thalamus (Vim) is known to exert a therapeutic effect on postural and kinetic tremor in patients with Essential Tremor (ET). For patients with DBS leads placed near the caudal border of Vim, however, there is an …
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The Effects of Deep Brain Stimulation on the Speech of Patients with Parkinson's Disease
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has received more attention in recent years as a treatment option for regulating the symptoms of Parkinson's disease. Previous studies of DBS documented consistent improvements in motor function but more variability in speech outcomes. …
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Performance on the Dementia Rating Scale-2 and deep brain stimulation screening : a retrospective review
Deep brain stimulation (DBS) is considered as a neurotherapeutic treatment option for Parkinson’s disease (PD) patients’ with medically intractable motor symptoms. With the increasing implementation of DBS surgery in South Africa, research on the neuropsychological prescreening criteria would be …
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Intrinsic Optical Imaging of Cortex During Deep Brain Stimulation: Parameters, Spatiotemporal Dynamics and Neurovascular Coupling
Deep brain stimulation (DBS) is clinically used to treat various movement disorders and has a potential to ameliorate other conditions such as depression, epilepsy etc. However, the mechanism through which DBS alleviates symptoms is not clear which prevents its efficient application and expansion …
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Wireless Sub-Cellular Sized Stimulators for Minimally Invasive Deep Brain Stimulation with High Spatiotemporal Resolution
Deep brain stimulation (DBS) has become a mainstream treatment for motor disorders associated with neurodegenerative conditions such as Parkinson’s disease (PD). The DBS device, often called the “pacemaker for the brain”, utilizes surgically implanted leads with 4-8 contacts points into the …
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A medicare benefit expansion: inpatient clinical and economic outcomes in deep brain stimulation for Parkinson's Disease
… mirror longer term outcomes for a CMS NCD for Deep Brain Stimulation (DBS) in Parkinson's Disease (PD). Methods: This observational study examined the inpatient clinical and economic outcomes associated with a CMS NCD for DBS in PD using Health Care Utilization Project (HCUP) retrospective data …
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Trajectory of Quality of Life in Advanced Parkinson's Patients Receiving Bilateral Subthalamic Nucleus Deep Brain Stimulation
… (QOL) in Parkinson's disease (PD) patients after Deep Brain Stimulation (DBS) neurosurgery generally improves between 3 to 24 months post-operatively. However, QOL beyond 2 year follow-up is generally unknown. This study examined the QOL in 16 advanced PD patients who received DBS at an average of …
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ESTIMATING PARAMETERS OF A MULTI-CLASS IZHIKEVICH NEURON MODEL TO INVESTIGATE THE MECHANISMS OF DEEP BRAIN STIMULATION
… efficient neural network model for the study of deep brain stimulation efficacy in the treatment of Parkinson's disease. An Izhikevich neuron model was used to accomplish this task and four classes of neurons were modeled. The parameters of each class were estimated using a genetic algorithm with …
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Mechanisms of Deep Brain Stimulation for the Treatment of Parkinson's Disease: Evidence from Experimental and Computational Studies
<p>Deep brain stimulation (DBS) is used to treat the motor symptoms of advanced Parkinson's disease (PD). Although this therapy has been widely applied, the mechanisms of action underlying its effectiveness remain unclear. The goal of this dissertation was to investigate the mechanisms underlying …
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Deep Brain Stimulation to Increase Generalized Arousal in Intact Mice and a Mouse Model of Traumatic Brain Injury
<p>Deep Brain Stimulation (DBS) is a promising neurosurgical technique that may be useful in promoting emergence to consciousness in minimally conscious state (MCS) patients. In this context, DBS of the central thalamus (CT/DBS) is intended to act as a surrogate input from the ascending arousal …
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Ο εν τω βάθει εγκεφαλικός ερεθισμός στην αντιμετώπιση της νευρογενούς ανορεξίας / The role of deep brain stimulation in the treatment of anorexia nervosa
Εισαγωγή: Η νευρογενής ανορεξία αποτελεί σοβαρή ψυχιατρική διαταραχή με υψηλή θνητότητα. Σε σοβαρή και μακράς διάρκειας νόσο, οι συμβατικές θεραπείες συχνά αποτυγχάνουν. Η εν τω βάθει εγκεφαλική διέγερση έχει αναδειχθεί ως δυνητική μέθοδος λειτουργικής ρύθμισης παθολογικών εγκεφαλικών κυκλωμάτων σε …
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