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Showing 1 to 2 of 2 for “"Decylubiquinone"”.

  1. Preclinical Study of Potential Antiglioma Novel Tetrahydroisoquinoline Analogs: Pharmacokinetics and Mechanism of Action

    … reversed the apoptotic effect of EDL-291. Decylubiquinone (dUb) can enhance caspase-3 activation as well as antiproliferative effect caused by EDL-291 treatment. Therefore, dUb could be a candidate companion drug of EDL-291 analogs in treating glioma.</p>

    tenn-hsc Repository record for Preclinical Study of Potential Antiglioma Novel Tetrahydroisoquinoline Analogs: Pharmacokinetics and Mechanism of Action (opens in a new tab)

  2. Biochemical Characterization of <i>Toxoplasma gondii</i> Type II NADH Dehydrogenases - Physiological Impact on Mitochondrial Functions and Energy Metabolism

    … oxidoreductase activities by using NADH and n-decylubiquinone as substrates. Additionally, TgNDH2-I could rescue the loss of complex I activity in Yarrowia, indicating that TgNDH2-I is expressed as an active enzyme. Furthermore, TgNDH2-I activity was effectively inhibited by HDQ with an IC50 at …

    goettingen Repository record for Biochemical Characterization of <i>Toxoplasma gondii</i> Type II NADH Dehydrogenases - Physiological Impact on Mitochondrial Functions and Energy Metabolism (opens in a new tab)